Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 18/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7083524 | 0.84 | HSD11B1 (0.57) | HSD11B1ALDH1A1MEN1KMT2ANR1I2 | |
| SCHEMBL7079477 | 0.83 | HSD11B1 (0.57) | HSD11B1MEN1KMT2ALMNA | |
| SCHEMBL7080251 | 0.81 | HSD11B1 (0.41) | HSD11B1ALDH1A1MEN1KMT2ANR1I2 | |
| Hydrochloric Acid SCHEMBL6900311 | 0.77 | HSD11B1 (0.60) | HSD11B1ALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL7079599 | 0.76 | HSD11B1 (0.52) | HSD11B1ALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL5104715 | 0.73 | HSD11B1 (1.00) | HSD11B1ALDH1A1MEN1KMT2A | |
| SCHEMBL7083527 | 0.73 | HSD11B1 (0.42) | HSD11B1MEN1KMT2ALMNA | |
| SCHEMBL5104987 | 0.72 | HSD11B1 (0.76) | HSD11B1ALDH1A1MEN1KMT2ANR1I2 | |
| SCHEMBL7085591 | 0.70 | KDM1A (0.43) | HSD11B1SMN1; SMN2 | |
| SCHEMBL5092048 | 0.69 | ALDH1A1 (0.70) | HSD11B1ALDH1A1MEN1KMT2ANR1I2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003064372-A1 | 2-ADAMANTYLALKYLAMINES AND THEIR USE IN THE TREATMENT OF CONDITIONS GENERALLY ASSOCIATED WITH ABNORMALITIES IN GLUTAMATERGIC TRANSMISSION | VERNALIS RESEARCH LIMITED (GB) | 2003-08-07 | — | — | WO | disclosed |