Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 10/20 | 0.42 |
| ▸ | HTR2C | P28335 | 2/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | CHRNA1 | P02708 | 1/20 | 0.33 |
| ▸ | CHRNG | P07510 | 1/20 | 0.33 |
| ▸ | CHRNB1 | P11230 | 1/20 | 0.33 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.33 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.33 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
| ▸ | CHRND | Q07001 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7083524 | 0.82 | HSD11B1 (0.57) | HSD11B1MEN1KMT2A | |
| SCHEMBL7079477 | 0.82 | HSD11B1 (0.57) | HSD11B1MEN1KMT2ALMNA | |
| SCHEMBL6685193 | 0.81 | HTR2C (0.46) | HSD11B1HTR2CHTR2AMEN1KMT2A | |
| SCHEMBL7085591 | 0.80 | KDM1A (0.43) | HSD11B1HTR2CHTR2ASLC6A2SLC6A3 | |
| Hydrochloric Acid SCHEMBL6896770 | 0.79 | HTR2C (0.48) | HSD11B1HTR2CHTR2AMEN1KMT2A | |
| SCHEMBL7079650 | 0.78 | FBP1 (0.41) | HSD11B1HTR2CHTR2AMEN1KMT2A | |
| SCHEMBL13216106 | 0.76 | HSD11B1 (0.71) | HSD11B1MEN1KMT2A | |
| SCHEMBL7080251 | 0.74 | HSD11B1 (0.41) | HSD11B1MEN1KMT2A | |
| SCHEMBL7082909 | 0.73 | HSD11B1 (0.57) | HSD11B1MEN1KMT2ALMNA | |
| SCHEMBL6898977 | 0.72 | CHRNA1 (0.43) | HSD11B1HTR2CHTR2AMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003064372-A1 | 2-ADAMANTYLALKYLAMINES AND THEIR USE IN THE TREATMENT OF CONDITIONS GENERALLY ASSOCIATED WITH ABNORMALITIES IN GLUTAMATERGIC TRANSMISSION | VERNALIS RESEARCH LIMITED (GB) | 2003-08-07 | — | — | WO | disclosed |