Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 2/20 | 0.43 |
| ▸ | HSD11B1 | P28845 | 4/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | KCNN4 | O15554 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
| ▸ | ACP3 | P15309 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | HTR2C | P28335 | 1/20 | 0.35 |
| ▸ | HTR2B | P41595 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7079469 | 0.80 | FBP1 (0.44) | KDM1AHSD11B1SLC6A4SLC6A3SLC6A2 | |
| SCHEMBL7083527 | 0.80 | HSD11B1 (0.42) | HSD11B1SLC6A3SLC6A2EPHX2HTR2A | |
| SCHEMBL7079477 | 0.78 | HSD11B1 (0.57) | HSD11B1 | |
| SCHEMBL7079057 | 0.75 | KDM1A (0.50) | KDM1ASLC6A4SLC6A3SLC6A2KCNN4 | |
| SCHEMBL7080251 | 0.68 | HSD11B1 (0.41) | HSD11B1 | |
| SCHEMBL7892396 | 0.66 | KDM1A (0.50) | KDM1ASLC6A4SLC6A3SLC6A2KCNN4 | |
| Hydrochloric Acid SCHEMBL6897921 | 0.63 | SLC6A3 (0.46) | KDM1AHSD11B1SLC6A3HTR2C | |
| SCHEMBL1420518 | 0.60 | KDM1A (0.59) | KDM1ASLC6A4SLC6A3SLC6A2KCNN4 | |
| SCHEMBL31557722 | 0.60 | OPRL1 (0.62) | KDM1ASLC6A4SMN1; SMN2OPRL1OPRM1 | |
| SCHEMBL10193786 | 0.60 | KDM1A (0.54) | KDM1ASLC6A4SLC6A3SLC6A2KCNN4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003064372-A1 | 2-ADAMANTYLALKYLAMINES AND THEIR USE IN THE TREATMENT OF CONDITIONS GENERALLY ASSOCIATED WITH ABNORMALITIES IN GLUTAMATERGIC TRANSMISSION | VERNALIS RESEARCH LIMITED (GB) | 2003-08-07 | — | — | WO | disclosed |