Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4C | Q9H3R0 | 4/20 | 0.69 |
| ▸ | PPARA | Q07869 | 2/20 | 0.64 |
| ▸ | STING1 | Q86WV6 | 1/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | NOX4 | Q9NPH5 | 2/20 | 0.56 |
| ▸ | EGFR | P00533 | 2/20 | 0.56 |
| ▸ | LCK | P06239 | 2/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.56 |
| ▸ | RGS12 | O14924 | 1/20 | 0.56 |
| ▸ | CAMKK2 | Q96RR4 | 1/20 | 0.56 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.46 |
| ▸ | CTSB | P07858 | 1/20 | 0.46 |
| ▸ | MMP9 | P14780 | 1/20 | 0.46 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.46 |
| ▸ | DNMT3B | Q9UBC3 | 1/20 | 0.46 |
| ▸ | DNMT3L | Q9UJW3 | 1/20 | 0.46 |
| ▸ | DNMT3A | Q9Y6K1 | 1/20 | 0.46 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.45 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7530660 | 0.89 | KDM4C (0.54) | KDM4CPPARASTING1ALDH1A1NOX4 | |
| SCHEMBL611490 | 0.83 | KDM4C (0.76) | KDM4CPPARASTING1ALDH1A1NOX4 | |
| SCHEMBL29532272 | 0.83 | KDM4C (0.76) | KDM4CPPARASTING1ALDH1A1NOX4 | |
| SCHEMBL609562 | 0.82 | PPARA (0.92) | KDM4CPPARASTING1ALDH1A1NOX4 | |
| SCHEMBL607997 | 0.82 | KDM4C (0.74) | KDM4CPPARASTING1ALDH1A1NOX4 | |
| SCHEMBL29388557 | 0.82 | KDM4C (0.74) | KDM4CPPARASTING1ALDH1A1NOX4 | |
| SCHEMBL29391100 | 0.82 | PPARA (0.92) | KDM4CPPARASTING1ALDH1A1NOX4 | |
| SCHEMBL31227881 | 0.81 | PPARA (0.80) | KDM4CPPARASTING1ALDH1A1NOX4 | |
| SCHEMBL31227771 | 0.81 | PPARA (0.80) | KDM4CPPARASTING1ALDH1A1NOX4 | |
| SCHEMBL10811982 | 0.79 | KDM4C (0.70) | KDM4CPPARASTING1ALDH1A1NOX4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030031715-A1 | Pharmaceutical applications of hydrotropic agents, polymers thereof, and hydrogels thereof | PURDUE RESEARCH FOUNDATION | 2003-02-13 | — | — | US | disclosed |
| WO-2002030466-A2 | PHARMACEUTICAL APPLICATIONS OF HYDROTROPIC AGENTS, POLYMERS THEREOF, AND HYDROGELS THEREOF | PURDUE RESEARCH FOUNDATION (US) | 2002-04-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030031715-A1 | Pharmaceutical applications of hydrotropic agents, polymers thereof, and hydrogels thereof | HMGB2, HTT, ABCG2 | KDM4C 4811/4885PPARA 960/4885STING1 4527/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.