Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 9/20 | 0.48 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.47 |
| ▸ | GAA | P10253 | 4/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | GFER | P55789 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.42 |
| ▸ | BRD4 | O60885 | 1/20 | 0.42 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL5169512 | 0.99 | ALOX5 (0.47) | ALOX5ADORA1ALDH1A1GAASMN1; SMN2 | |
| SCHEMBL7083935 | 0.99 | ALOX5 (0.49) | ALOX5ADORA1ALDH1A1GAASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL5166124 | 0.98 | ALOX5 (0.48) | ALOX5ADORA1ALDH1A1GAASMN1; SMN2 | |
| SCHEMBL5166144 | 0.84 | ADORA1 (0.57) | ALOX5ADORA1ALDH1A1GAASMN1; SMN2 | |
| SCHEMBL5165614 | 0.83 | GAA (0.67) | ALOX5ADORA1ALDH1A1GAASMN1; SMN2 | |
| SCHEMBL2988604 | 0.83 | ALOX5 (0.72) | ALOX5ADORA1ALDH1A1GAASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL5167299 | 0.82 | GAA (0.65) | ALOX5ADORA1ALDH1A1GAASMN1; SMN2 | |
| SCHEMBL5165259 | 0.81 | PRKAB2 (0.47) | ALOX5ADORA1ALDH1A1GAASMN1; SMN2 | |
| SCHEMBL5168292 | 0.80 | PABPC1 (0.66) | ALOX5ADORA1ALDH1A1GAASMN1; SMN2 | |
| SCHEMBL5166137 | 0.78 | ALDH1A1 (0.49) | ALOX5ADORA1ALDH1A1GAASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1326613-A1 | USE OF SUBSTITUTED IMIDAZO 1,2-A]PYRIDINE-, IMIDAZO 1,2-A]PYRIMIDINE AND IMIDAZO 1,2-A]PYRAZINE-3-YL-AMINE DERIVATIVES FOR PRODUCING NOS-INHIBITING MEDICAMENTS | Grünenthal GmbH (DE) | 2003-07-16 | — | — | EP | disclosed |
| WO-2002030428-A1 | USE OF SUBSTITUTED IMIDAZO[1,2-A]PYRIDINE-, IMIDAZO[1,2-A]PYRIMIDINE AND IMIDAZO[1,2-A]PYRAZINE-3-YL-AMINE DERIVATIVES FOR PRODUCING NOS-INHIBITING MEDICAMENTS | Grünenthal GmbH (DE) | 2002-04-18 | — | — | WO | disclosed |