SCHEMBL708336

SCHEMBL708336

NC(CO)C(CO)(CO)S(=O)(=O)O

nearest known ligand 0.30

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
TP53 P04637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3797120 0.82 TP53 (0.36) TP53
SCHEMBL6510727 0.74
SCHEMBL28437230 0.71 TP53 (0.35) TP53
SCHEMBL12489483 0.69
Sulfuric Acid SCHEMBL1508822 0.68 CA5A (0.40) TP53
Sulfuric Acid SCHEMBL1508546 0.68 CA5A (0.40) TP53
L-Alaninol SCHEMBL1343064 0.66 TP53 (0.52) TP53
SCHEMBL21496249 0.65 TP53 (0.33) TP53
Tromethamine SCHEMBL1508805 0.62 LMNA (0.67)
Tromethamine SCHEMBL4939766 0.62 LMNA (0.67)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 79 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7820425-B2 Method of cryopreserving selected sperm cells XY, LLC (US) 2010-10-26 US claimed
EP-1557087-A1 Method of cryopreserving selected sperm cells XY, Inc. (US) 2005-07-27 EP claimed
EP-0592242-B1 Fibrin sealant compositions and method for utilizing same SQUIBB & SONS INC (US) 2003-07-09 EP claimed
US-5750657-A Methods and compositions using fibrin monomer to make a fibrin sealant BRISTOL-MYERS SQUIBB COMPANY (US) 1998-05-12 US claimed
EP-0592242-A1 Fibrin sealant compositions and method for utilizing same E.R. SQUIBB & SONS, INC. (US) 1994-04-13 EP claimed
EP-2023941-B1 PROTEIN CROSSLINKERS, CROSSLINKING METHODS AND APPLICATIONS THEREOF INCEPT LLC (US) 2016-12-21 EP disclosed
US-9498557-B2 Crosslinking methods and applications thereof INCEPT, LLC (US) 2016-11-22 US disclosed
CN-103585136-A Methods and compositions for delivery of catecholic butanes for treatment of tumors UNIV JOHNS HOPKINS 2014-02-19 CN disclosed
US-8652821-B2 Stabilized protease-containing solutions for purifying RNA-free DNA BIO-RAD LABORATORIES, INC. (US) 2014-02-18 US disclosed
US-20120156284-A1 ENHANCED BIOLOGICAL AUTOLOGOUS TISSUE ADHESIVE COMPOSITION AND METHODS OF PREPARATION AND USE SPINAL RESTORATION, INC. 2012-06-21 US disclosed
US-20120100597-A1 STABILIZED PROTEASE-CONTAINING SOLUTIONS Bio-Ras Laboratories, Inc. (US) 2012-04-26 US disclosed
WO-2012054613-A2 STABILIZED PROTEASE-CONTAINING SOLUTIONS BIO-RAD LABORATORIES, INC. (US) 2012-04-26 WO disclosed
EP-0638168-A4 CAPILLARY ELECTROPHORESIS MOLECULAR WEIGHT SEPARATION OF BIOMOLECULES USING A POLYMER-CONTAINING SOLUTION. APPLIED BIOSYSTEMS (US) 1995-07-19 EP disclosed
WO-1995016911-A1 POLYMERS FOR SEPARATION OF BIOMOLECULES BY CAPILLARY ELECTROPHORESIS PERKIN-ELMER CORPORATION (US) 1995-06-22 WO disclosed
WO-1995016910-A1 UNCHARGED POLYMERS FOR SEPARATION OF BIOMOLECULES BY CAPILLARY ELECTROPHORESIS PERKIN-ELMER CORPORATION (US) 1995-06-22 WO disclosed
EP-0654078-A1 A THROMBIN BLOOD FRACTION FOR USE IN A MEDICAL PROCEDURE E.R. SQUIBB & SONS, INC. (US) 1995-05-24 EP disclosed
EP-0638168-A1 CAPILLARY ELECTROPHORESIS MOLECULAR WEIGHT SEPARATION OF BIOMOLECULES USING A POLYMER-CONTAINING SOLUTION THE PERKIN-ELMER CORPORATION (US) 1995-02-15 EP disclosed
EP-0592242-A1 Fibrin sealant compositions and method for utilizing same E.R. SQUIBB & SONS, INC. (US) 1994-04-13 EP disclosed
WO-1994000566-A1 A THROMBIN BLOOD FRACTION FOR USE IN A MEDICAL PROCEDURE E.R. SQUIBB & SONS INC. (US) 1994-01-06 WO disclosed
WO-1993022665-A1 CAPILLARY ELECTROPHORESIS MOLECULAR WEIGHT SEPARATION OF BIOMOLECULES USING A POLYMER-CONTAINING SOLUTION APPLIED BIOSYSTEMS, INC. (US) 1993-11-11 WO disclosed