SCHEMBL7083434

SCHEMBL7083434

CCCCc1ccc(O)c(-c2cc(O)cc(O)c2)c1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CNR1 P21554 1/20 0.58
CNR2 P34972 1/20 0.58
ALOX5 P09917 2/20 0.54
PTGS2 P35354 4/20 0.50
CYP3A4 P08684 2/20 0.50
NPC1 O15118 1/20 0.49
HPGD P15428 1/20 0.49
MAPK1 P28482 1/20 0.49
HTT P42858 1/20 0.49
RAB9A P51151 1/20 0.49
NPSR1 Q6W5P4 1/20 0.49
GABRA1 P14867 1/20 0.47
GABRB2 P47870 1/20 0.47
BACE1 P56817 2/20 0.46
GPR84 Q9NQS5 1/20 0.46
KAT8 Q9H7Z6 2/20 0.45
ESR1 P03372 2/20 0.44
ADRA2A P08913 2/20 0.44
ADORA3 P0DMS8 2/20 0.44
TACR2 P21452 2/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7080953 0.90 CNR1 (0.72) CNR1CNR2ALOX5PTGS2CYP3A4
SCHEMBL9818748 0.87 ALOX5 (0.58) CNR1CNR2ALOX5PTGS2CYP3A4
SCHEMBL28653265 0.86 CNR1 (0.61) CNR1CNR2ALOX5PTGS2CYP3A4
SCHEMBL723543 0.86 CNR1 (0.77) CNR1CNR2ALOX5PTGS2CYP3A4
SCHEMBL4591101 0.83 BACE1 (0.66) CNR1CNR2ALOX5NPC1HPGD
SCHEMBL7083937 0.82 TRPA1 (0.55) CNR1CNR2ALOX5NPC1HPGD
SCHEMBL29138357 0.82 BACE1 (0.69) CNR1CNR2ALOX5NPC1HPGD
SCHEMBL29138315 0.81 ALOX5 (0.55) CNR1CNR2ALOX5NPC1HPGD
SCHEMBL1704200 0.81 ALOX5 (0.77) CNR1CNR2ALOX5NPC1HPGD
SCHEMBL27658819 0.81 CNR1 (0.54) CNR1CNR2ALOX5PTGS2CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20030139479-A1 Non-halogenated biphenyl triol compounds, antimicrobial compositions containing the same, and methods of using the same WARNER-LAMBERT COMPANY 2003-07-24 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030139479-A1 Non-halogenated biphenyl triol compounds, antimicrobial compositions containing the same, and methods of using the same AS3MT, PTPN1, NONO CNR1 4618/4885CNR2 4624/4885ALOX5 1169/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.