Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.58 |
| ▸ | RAB9A | P51151 | 4/20 | 0.58 |
| ▸ | NPC1 | O15118 | 2/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.51 |
| ▸ | MEN1 | O00255 | 4/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | CASP3 | P42574 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.51 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.51 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | CRHBP | P24387 | 1/20 | 0.46 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.46 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6799338 | 0.89 | RAB9A (0.70) | MAPTRAB9ANPC1SMN1; SMN2KMT2A | |
| SCHEMBL6499921 | 0.86 | L3MBTL1 (0.46) | MAPTRAB9ANPC1SMN1; SMN2KMT2A | |
| SCHEMBL7079364 | 0.84 | AOC3 (0.59) | RAB9ANPC1SMN1; SMN2KMT2AALDH1A1 | |
| SCHEMBL3931075 | 0.82 | AOC3 (0.64) | RAB9ASMN1; SMN2KMT2AMEN1AOC3 | |
| SCHEMBL21382353 | 0.80 | RAB9A (0.64) | MAPTRAB9ANPC1SMN1; SMN2KMT2A | |
| SCHEMBL6489114 | 0.80 | SMN1; SMN2 (0.51) | MAPTRAB9ASMN1; SMN2KMT2AMEN1 | |
| SCHEMBL9047133 | 0.77 | RAB9A (0.60) | MAPTRAB9ANPC1SMN1; SMN2KMT2A | |
| SCHEMBL7083523 | 0.74 | RAB9A (0.59) | MAPTRAB9ANPC1KMT2AMEN1 | |
| SCHEMBL4295973 | 0.74 | SMN1; SMN2 (0.61) | RAB9ANPC1SMN1; SMN2KMT2AALDH1A1 | |
| SCHEMBL6488833 | 0.74 | SIRT1 (0.40) | MAPTRAB9ANPC1SMN1; SMN2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1326835-A1 | BENZAMIDE COMPOUNDS AS APO B SECRETION INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2003-07-16 | — | — | EP | disclosed |
| WO-2002028835-A1 | BENZAMIDE COMPOUNDS AS APO B SECRETION INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-04-11 | — | — | WO | disclosed |