Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.62 |
| ▸ | MAPT | P10636 | 3/20 | 0.62 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.62 |
| ▸ | PPARA | Q07869 | 1/20 | 0.54 |
| ▸ | FFAR4 | Q5NUL3 | 3/20 | 0.51 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.45 |
| ▸ | GCGR | P47871 | 1/20 | 0.45 |
| ▸ | CNR2 | P34972 | 1/20 | 0.44 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.44 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.43 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.43 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | STS | P08842 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3182853 | 0.80 | NPC1 (0.68) | LMNAMAPTL3MBTL1PPARAFFAR4 | |
| SCHEMBL9730131 | 0.79 | PPARA (0.69) | LMNAMAPTL3MBTL1PPARAFFAR4 | |
| SCHEMBL29986971 | 0.78 | MAPT (0.57) | LMNAMAPTL3MBTL1HPGDPOLB | |
| SCHEMBL322169 | 0.78 | MAPT (0.57) | LMNAMAPTL3MBTL1HPGDPOLB | |
| SCHEMBL18675949 | 0.78 | KMT2A (0.56) | LMNAL3MBTL1FFAR4HPGDPOLB | |
| SCHEMBL28095416 | 0.77 | MAPT (0.55) | LMNAMAPTL3MBTL1HPGDPOLB | |
| SCHEMBL27754115 | 0.77 | TUBB4A (0.43) | LMNAL3MBTL1FFAR4HPGD | |
| SCHEMBL12427902 | 0.76 | NPC1 (0.60) | LMNAMAPTHPGDPOLBKDM4E | |
| SCHEMBL28872783 | 0.76 | MAPT (0.58) | LMNAMAPTL3MBTL1HPGDPOLB | |
| SCHEMBL18675951 | 0.76 | KMT2A (0.57) | LMNAL3MBTL1FFAR4HPGDPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003068806-A1 | SOLID PHASE PEPTIDE SYNTHESIS ON SILICA | JOHNSON MATTHEY PLC (GB) | 2003-08-21 | — | — | WO | claimed |
| WO-2003068806-A1 | SOLID PHASE PEPTIDE SYNTHESIS ON SILICA | JOHNSON MATTHEY PLC (GB) | 2003-08-21 | — | — | WO | disclosed |