Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 7/20 | 0.60 |
| ▸ | RAB9A | P51151 | 7/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.60 |
| ▸ | MAPT | P10636 | 4/20 | 0.60 |
| ▸ | TP53 | P04637 | 3/20 | 0.60 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.60 |
| ▸ | POLB | P06746 | 3/20 | 0.53 |
| ▸ | MEN1 | O00255 | 4/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12427927 | 0.91 | NPC1 (0.60) | NPC1RAB9ASMN1; SMN2MAPTTP53 | |
| SCHEMBL12427905 | 0.89 | MAPT (0.73) | NPC1RAB9ASMN1; SMN2MAPTTP53 | |
| SCHEMBL2282734 | 0.83 | RAB9A (0.62) | NPC1RAB9ASMN1; SMN2MAPTTP53 | |
| SCHEMBL2060717 | 0.81 | NPC1 (0.60) | NPC1RAB9ASMN1; SMN2MAPTTP53 | |
| SCHEMBL27739490 | 0.81 | RAB9A (0.76) | NPC1RAB9ASMN1; SMN2MAPTTP53 | |
| SCHEMBL11311038 | 0.79 | RAB9A (0.70) | NPC1RAB9ASMN1; SMN2MAPTTP53 | |
| SCHEMBL2196772 | 0.78 | MEN1 (0.69) | NPC1RAB9ASMN1; SMN2MAPTTP53 | |
| SCHEMBL19077957 | 0.76 | MAPT (0.62) | NPC1RAB9ASMN1; SMN2MAPTTP53 | |
| SCHEMBL7083549 | 0.76 | LMNA (0.62) | MAPTPOLBHPGDKDM4ELMNA | |
| SCHEMBL22833904 | 0.76 | NPC1 (0.86) | NPC1RAB9ASMN1; SMN2MAPTTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1246792-B1 | COMPOUNDS AND COMPOSITIONS FOR DELIVERING ACTIVE AGENTS | EMISPHERE TECH INC (US) | 2014-08-13 | — | — | EP | disclosed |
| US-7977506-B2 | Amino acid for delivering active materials; bioavailability | EMISPHERE TECHNOLOGIES, INC. (US) | 2011-07-12 | — | — | US | disclosed |
| US-7977506-B2 | Amino acid for delivering active materials; bioavailability | EMISPHERE TECHNOLOGIES, INC. (US) | 2011-07-12 | — | — | US | disclosed |
| US-20070087958-A1 | COMPOUNDS AND COMPOSITIONS FOR DELIVERING ACTIVE AGENTS | EMISPHERE TECHNOLOGIES, INC. (US) | 2007-04-19 | — | — | US | disclosed |
| US-20070087958-A1 | COMPOUNDS AND COMPOSITIONS FOR DELIVERING ACTIVE AGENTS | EMISPHERE TECHNOLOGIES, INC. (US) | 2007-04-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070087958-A1 | COMPOUNDS AND COMPOSITIONS FOR DELIVERING ACTIVE AGENTS | SERPINB1, ELANE, MMP8 | NPC1 52/4885RAB9A 2126/4885SMN1; SMN2 119/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.