Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 5/20 | 0.55 |
| ▸ | MAOB | P27338 | 4/20 | 0.55 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.55 |
| ▸ | SDHA | P31040 | 2/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | CALML3 | P27482 | 1/20 | 0.55 |
| ▸ | F10 | P00742 | 5/20 | 0.42 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28594531 | 1.00 | MAOA (0.55) | MAOAMAOBPTGS1SDHALMNA | |
| SCHEMBL7537310 | 1.00 | MAOA (0.55) | MAOAMAOBPTGS1SDHALMNA | |
| SCHEMBL28594529 | 0.86 | MAOA (0.62) | MAOAMAOBPTGS1SDHALMNA | |
| SCHEMBL7537313 | 0.86 | MAOA (0.62) | MAOAMAOBPTGS1SDHALMNA | |
| SCHEMBL483916 | 0.85 | MAOA (0.61) | MAOAMAOBPTGS1SDHALMNA | |
| SCHEMBL27707418 | 0.85 | MAOA (0.61) | MAOAMAOBPTGS1SDHALMNA | |
| SCHEMBL27875818 | 0.85 | MAOA (0.61) | MAOAMAOBPTGS1SDHALMNA | |
| SCHEMBL15141607 | 0.84 | MAOA (0.43) | MAOAMAOBPTGS1SDHALMNA | |
| SCHEMBL28998570 | 0.84 | MAOB (0.68) | MAOAMAOBPTGS1SDHALMNA | |
| SCHEMBL27801851 | 0.84 | MAOB (0.68) | MAOAMAOBPTGS1SDHALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102174027-A | New crystal form of linezolid and preparation method and application thereof | Chengdu zihao pharmaceutical co ltd | 2011-09-07 | — | — | CN | claimed |
| US-20030065219-A1 | PROCESS TO PRODUCE OXAZOLIDINONES | PHARMACIA & UPJOHN COMPANY | 2003-04-03 | — | — | US | claimed |
| CN-109444294-B | High performance liquid chromatography method for separating linezolid and chiral isomer thereof | SUZHOU LAIAO BIOTECHNOLOGY Co.,Ltd. (CN) | 2021-06-22 | — | — | CN | disclosed |
| CN-103025730-A | Method for preparing linezolid | UNIV INDIANA RES & TECH CORP | 2013-04-03 | — | — | CN | disclosed |
| CN-102675239-A | Method for preparing linezolid crystal form I | KAIYUAN HENGTAI CHEMICAL CO LTD | 2012-09-19 | — | — | CN | disclosed |
| CN-102174027-A | New crystal form of linezolid and preparation method and application thereof | Chengdu zihao pharmaceutical co ltd | 2011-09-07 | — | — | CN | disclosed |
| US-6562844-B2 | Attaching an olefin to a solid support; oxidizing the olefin to provide an epoxide functionality; opening the epoxide with an amine to form an amino alcohol; cyclizing the amino alcohol using a phosgene equivalent | PHARMACIA & UPJOHN COMPANY | 2003-05-13 | — | — | US | disclosed |
| US-20020183371-A1 | Oxazolidinone combinatorial libraries, compositions and methods of preparation | GORDEEV MIKHAIL F (US) | 2002-12-05 | — | — | US | disclosed |
| CN-1288462-A | Oxazolidinone combinatorial libraries, compositions and method of prepn. | UPJOHN CO (US) | 2001-03-21 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030065219-A1 | PROCESS TO PRODUCE OXAZOLIDINONES | ADH1A, ADH5, ADH1C | MAOA 156/4885MAOB 189/4885PTGS1 2552/4885 |
| US-20020183371-A1 | Oxazolidinone combinatorial libraries, compositions and methods of preparation | PAICS, CDK4, OXA1L | MAOA 1267/4885MAOB 1298/4885PTGS1 4238/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.