Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | SYK | P43405 | 2/20 | 0.38 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.38 |
| ▸ | INCENP | Q9NQS7 | 1/20 | 0.38 |
| ▸ | TACR1 | P25103 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.35 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.35 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.35 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.35 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.35 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.35 |
| ▸ | SMO | Q99835 | 1/20 | 0.34 |
| ▸ | MGAT2 | Q10469 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6789334 | 0.77 | SMO (0.56) | CYP1A2CYP2C9CYP2C19SMOKDM4E | |
| SCHEMBL7085043 | 0.75 | LMNA (0.45) | HTTLMNATACR1CYP1A2CYP2C19 | |
| SCHEMBL7083795 | 0.75 | HTR2A (0.42) | HTTLMNASYKAURKBINCENP | |
| SCHEMBL7083954 | 0.75 | LMNA (0.43) | HTTLMNASYKAURKBINCENP | |
| SCHEMBL7085682 | 0.74 | SMN1; SMN2 (0.46) | HTTLMNASYKAURKBINCENP | |
| SCHEMBL7083798 | 0.73 | GRM4 (0.44) | HTTLMNACYP1A2CYP2C9CYP2C19 | |
| SCHEMBL6504077 | 0.70 | SMO (0.48) | HTTSYKCYP1A2CYP2C9CYP2C19 | |
| SCHEMBL7080553 | 0.68 | CHRNB2 (0.44) | LMNATACR1CHRNB2CHRNB4CHRNA3 | |
| SCHEMBL7083816 | 0.67 | LMNA (0.48) | HTTLMNACYP1A2CHRNB2CHRNB4 | |
| SCHEMBL6795346 | 0.66 | SMO (0.59) | SMO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1326835-A1 | BENZAMIDE COMPOUNDS AS APO B SECRETION INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2003-07-16 | — | — | EP | disclosed |
| WO-2002028835-A1 | BENZAMIDE COMPOUNDS AS APO B SECRETION INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-04-11 | — | — | WO | disclosed |