Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.38 |
| ▸ | MEN1 | O00255 | 4/20 | 0.38 |
| ▸ | RAB9A | P51151 | 4/20 | 0.38 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.37 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.37 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.37 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.37 |
| ▸ | TACR1 | P25103 | 2/20 | 0.36 |
| ▸ | SYK | P43405 | 1/20 | 0.36 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.36 |
| ▸ | INCENP | Q9NQS7 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7085043 | 0.85 | LMNA (0.45) | SMN1; SMN2CYP1A2CYP2C19LMNAHTT | |
| SCHEMBL7083954 | 0.82 | LMNA (0.43) | SMN1; SMN2CYP1A2CYP2C19LMNAHTT | |
| SCHEMBL7083793 | 0.74 | HTT (0.39) | CYP1A2CYP2C19LMNAHTTCHRNB2 | |
| SCHEMBL6788349 | 0.73 | SMO (0.59) | LMNAHTTALDH1A1SMO | |
| SCHEMBL28456749 | 0.72 | SMN1; SMN2 (0.81) | SMN1; SMN2CYP1A2CYP2C19LMNAKMT2A | |
| SCHEMBL7083816 | 0.69 | LMNA (0.48) | SMN1; SMN2CYP1A2LMNAHTTKMT2A | |
| SCHEMBL7086831 | 0.69 | CHRNB2 (0.43) | SMN1; SMN2CYP1A2CYP2C19LMNAHTT | |
| Hydrochloric Acid SCHEMBL9701760 | 0.69 | RAB9A (0.70) | SMN1; SMN2CYP1A2CYP2C19LMNAHTT | |
| SCHEMBL7080553 | 0.68 | CHRNB2 (0.44) | LMNAKMT2AMEN1RAB9ACHRNB2 | |
| SCHEMBL7085677 | 0.68 | LMNA (0.45) | SMN1; SMN2CYP1A2CYP2C19LMNARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1326835-A1 | BENZAMIDE COMPOUNDS AS APO B SECRETION INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2003-07-16 | — | — | EP | disclosed |
| WO-2002028835-A1 | BENZAMIDE COMPOUNDS AS APO B SECRETION INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-04-11 | — | — | WO | disclosed |