Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.56 |
| ▸ | RAB9A | P51151 | 1/20 | 0.56 |
| ▸ | MYC | P01106 | 1/20 | 0.56 |
| ▸ | MAX | P61244 | 1/20 | 0.56 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.51 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6536287 | 0.90 | ALDH1A1 (0.53) | POLBRAB9AMYCMAXPTGS2 | |
| SCHEMBL6641665 | 0.87 | MYC (0.66) | POLBRAB9AMYCMAXPTGDR2 | |
| SCHEMBL6795849 | 0.81 | ALDH1A1 (0.53) | POLBRAB9AMYCMAXMAPT | |
| SCHEMBL15229768 | 0.81 | MYC (0.55) | POLBRAB9AMYCMAXPTGDR2 | |
| SCHEMBL1984348 | 0.81 | POLB (0.52) | POLBRAB9AMYCMAXPTGDR2 | |
| SCHEMBL31590561 | 0.80 | ALDH1A1 (0.55) | RAB9AMAPTMEN1KMT2ATSHR | |
| SCHEMBL6536346 | 0.79 | MYC (0.56) | POLBRAB9AMYCMAXMAPT | |
| SCHEMBL8382506 | 0.78 | POLB (0.64) | POLBRAB9AMYCMAXPTGDR2 | |
| SCHEMBL10694655 | 0.78 | ALDH1A1 (0.57) | POLBMAPTMEN1KMT2ATSHR | |
| SCHEMBL6391559 | 0.78 | PTGS2 (0.69) | POLBRAB9AMYCMAXPTGDR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1326835-A1 | BENZAMIDE COMPOUNDS AS APO B SECRETION INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2003-07-16 | — | — | EP | disclosed |
| WO-2002028835-A1 | BENZAMIDE COMPOUNDS AS APO B SECRETION INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-04-11 | — | — | WO | disclosed |
| US-4052444-A | DIAZO COUPLERS FOR MONOAZO DYES | HOECHST AKTIENGESELLSCHAFT (DT) | 1977-10-04 | — | — | US | disclosed |