Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 4/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.56 |
| ▸ | HTR2A | P28223 | 2/20 | 0.47 |
| ▸ | HTR2C | P28335 | 1/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | PPARG | P37231 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | NAT1 | P18440 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.42 |
| ▸ | LOX | P28300 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6853680 | 0.91 | ALDH1A1 (0.48) | HTR6ALDH1A1CYP2A6PKMTSHR | |
| SCHEMBL5274424 | 0.86 | HTR6 (0.49) | HTR6ALDH1A1CYP2A6HTR2AHTR2C | |
| SCHEMBL6853554 | 0.84 | CA12 (0.49) | HTR6ALDH1A1CYP2A6HTR2AHTR2C | |
| SCHEMBL5051390 | 0.83 | HTR6 (0.93) | HTR6ALDH1A1MAPTSMN1; SMN2POLB | |
| SCHEMBL2538638 | 0.81 | HTR6 (0.56) | HTR6ALDH1A1CYP2A6HTR2AHTR2C | |
| SCHEMBL7958473 | 0.81 | LMNA (0.52) | L3MBTL1TSHRLOX | |
| (Phenylsulfonyl)Benzene SCHEMBL9405432 | 0.80 | HTR6 (0.78) | HTR6ALDH1A1MAPTSMN1; SMN2POLB | |
| SCHEMBL25184892 | 0.80 | ALDH1A1 (0.54) | HTR6ALDH1A1CYP2A6PPARGNAT1 | |
| SCHEMBL2029529 | 0.80 | GAA (0.70) | ALDH1A1CYP2A6L3MBTL1MAPTSMN1; SMN2 | |
| SCHEMBL1466220 | 0.80 | HTR2A (0.54) | HTR2AHTR2CKCNH2HSD11B1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 95 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12060365-B2 | Cycloalkane-1,3-diamine derivative | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2024-08-13 | — | — | US | disclosed |
| EP-3189049-B1 | PHTHALAZINE DERIVATIVES OF FORMULA (I) AS PCAF AND GCN5 INHIBITORS FOR USE IN THE TREATMENT OF CANCER | GENENTECH INC (US) | 2024-03-20 | — | — | EP | disclosed |
| EP-3892278-B1 | CYCLOALKANE-1,3-DIAMINE DERIVATIVE | DAIICHI SANKYO CO LTD (JP) | 2024-02-28 | — | — | EP | disclosed |
| US-20230074669-A1 | CYCLOALKANE-1,3-DIAMINE DERIVATIVE | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2023-03-09 | — | — | US | disclosed |
| US-20230074669-A1 | CYCLOALKANE-1,3-DIAMINE DERIVATIVE | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2023-03-09 | — | — | US | disclosed |
| US-20230030720-A1 | CYCLOALKANE-1,3-DIAMINE DERIVATIVE | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2023-02-02 | — | — | US | disclosed |
| US-11236106-B2 | Cycloalkane-1,3-diamine derivative | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2022-02-01 | — | — | US | disclosed |
| US-11236106-B2 | Cycloalkane-1,3-diamine derivative | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2022-02-01 | — | — | US | disclosed |
| EP-3189046-B1 | THERAPEUTIC COMPOUNDS AND USES THEREOF | GENENTECH INC (US) | 2020-08-26 | — | — | EP | disclosed |
| US-10358437-B2 | Therapeutic compounds and uses thereof | GENENTECH, INC. (US) | 2019-07-23 | — | — | US | disclosed |
| US-4889932-A | THERMOGRAPHY; COATINGS | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1989-12-26 | — | — | US | disclosed |
| EP-0181085-B1 | STABILIZED LEUCO PHENAZINE DYES AND THEIR USE IN AN IMAGING SYSTEM | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1989-08-09 | — | — | EP | disclosed |
| US-4647525-A | Stabilized leuco phenazine dyes and their use in an imaging system | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1987-03-03 | — | — | US | disclosed |
| EP-0181085-A1 | Stabilized leuco phenazine dyes and their use in an imaging system | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1986-05-14 | — | — | EP | disclosed |
| US-4002616-A | POLYESTERS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1977-01-11 | — | — | US | disclosed |
| US-3966678-A | Maleic anhydride-polyaldimine prepolymers | RHONE-POULENC S.A. (FR) | 1976-06-29 | — | — | US | disclosed |
| US-3962220-A | ONE-STEP, AROMATIC ALDEHYDES, ACETIC ACID | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1976-06-08 | — | — | US | disclosed |
| US-3962221-A | CONDENSATION, REDUCTION, OXIDATION | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1976-06-08 | — | — | US | disclosed |
| US-3956395-A | Distyrylbenzene disulfone derivatives | MEYER HANS RUDOLF | 1976-05-11 | — | — | US | disclosed |
| US-3931142-A | Heterocyclic containing disazo compounds | CIBA-GEIGY AG (CH) | 1976-01-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11236106-B2 | Cycloalkane-1,3-diamine derivative | MLLT1, MEN1, MLLT3 | HTR6 4401/4885ALDH1A1 3327/4885CYP2A6 4166/4885 |
| US-12060365-B2 | Cycloalkane-1,3-diamine derivative | MLLT1, MEN1, MLLT3 | HTR6 4401/4885ALDH1A1 3327/4885CYP2A6 4166/4885 |
| US-10358437-B2 | Therapeutic compounds and uses thereof | PKD1, NHERF1, HDAC10 | HTR6 2006/4885ALDH1A1 782/4885CYP2A6 1575/4885 |
| US-20230030720-A1 | CYCLOALKANE-1,3-DIAMINE DERIVATIVE | MLLT1, MEN1, MLLT3 | HTR6 4401/4885ALDH1A1 3327/4885CYP2A6 4166/4885 |
| US-20230074669-A1 | CYCLOALKANE-1,3-DIAMINE DERIVATIVE | MLLT1, MEN1, MLLT3 | HTR6 4401/4885ALDH1A1 3327/4885CYP2A6 4166/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.