Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NTRK1 | P04629 | 5/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.40 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.40 |
| ▸ | TACR1 | P25103 | 1/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 3/20 | 0.38 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.38 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.38 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.38 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.38 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.37 |
| ▸ | SMO | Q99835 | 1/20 | 0.37 |
| ▸ | SRPK1 | Q96SB4 | 1/20 | 0.37 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6794057 | 0.89 | SMO (0.45) | NTRK1CHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL7083456 | 0.82 | SORT1 (0.46) | NTRK1ALDH1A1SORT1SCN9ASCN5A | |
| SCHEMBL6793989 | 0.77 | TRPV1 (0.48) | ALDH1A1SORT1SMO | |
| SCHEMBL6789589 | 0.76 | TRPV1 (0.51) | ALDH1A1SMO | |
| SCHEMBL7138452 | 0.74 | ALDH1A1 (0.42) | NTRK1ALDH1A1RXFP1 | |
| SCHEMBL7134201 | 0.72 | LRRK2 (0.51) | SORT1LRRK2 | |
| SCHEMBL7080705 | 0.71 | SMO (0.49) | SORT1SMOLRRK2 | |
| SCHEMBL7083654 | 0.70 | SORT1 (0.45) | ALDH1A1SORT1RXFP1SMO | |
| SCHEMBL7087226 | 0.70 | SMO (0.49) | ALDH1A1SORT1RXFP1SMOSRPK1 | |
| SCHEMBL28675083 | 0.69 | PTGDR2 (0.50) | NTRK1ALDH1A1TACR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1326835-A1 | BENZAMIDE COMPOUNDS AS APO B SECRETION INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2003-07-16 | — | — | EP | disclosed |
| WO-2002028835-A1 | BENZAMIDE COMPOUNDS AS APO B SECRETION INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-04-11 | — | — | WO | disclosed |