Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.50 |
| ▸ | SCN1A | P35498 | 5/20 | 0.49 |
| ▸ | SCN2A | Q99250 | 5/20 | 0.49 |
| ▸ | SCN3A | Q9NY46 | 5/20 | 0.49 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.49 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.49 |
| ▸ | CHRNB2 | P17787 | 3/20 | 0.45 |
| ▸ | CHRNB4 | P30926 | 3/20 | 0.45 |
| ▸ | CHRNA3 | P32297 | 3/20 | 0.45 |
| ▸ | CHRNA4 | P43681 | 3/20 | 0.45 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.44 |
| ▸ | HNF4A | P41235 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10499603 | 0.83 | BCAT2 (0.50) | MEN1KMT2ASMN1; SMN2BCAT2SCN1A | |
| SCHEMBL9800704 | 0.78 | LMNA (0.62) | KMT2ASMN1; SMN2GAASLC6A2ALDH1A1 | |
| SCHEMBL1775832 | 0.78 | SLC6A3 (0.74) | MEN1KMT2ASMN1; SMN2BCAT2SCN1A | |
| SCHEMBL28104264 | 0.78 | BCAT2 (0.57) | MEN1KMT2ASMN1; SMN2BCAT2SCN1A | |
| SCHEMBL9790236 | 0.77 | BCAT2 (0.61) | MEN1KMT2ASMN1; SMN2BCAT2SCN1A | |
| SCHEMBL28444799 | 0.77 | BCAT2 (0.61) | MEN1KMT2ASMN1; SMN2BCAT2SCN1A | |
| Phosphine SCHEMBL11469830 | 0.77 | SLC6A3 (0.72) | MEN1KMT2ASMN1; SMN2BCAT2SCN1A | |
| SCHEMBL28698767 | 0.77 | MAPT (0.47) | MEN1KMT2ATSHR | |
| Bicarbonate SCHEMBL27467504 | 0.77 | SLC6A3 (0.72) | MEN1KMT2ASMN1; SMN2BCAT2SCN1A | |
| SCHEMBL7084393 | 0.77 | HNF4A (0.56) | MEN1KMT2ASMN1; SMN2BCAT2CHRNB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1326835-A1 | BENZAMIDE COMPOUNDS AS APO B SECRETION INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2003-07-16 | — | — | EP | disclosed |
| WO-2002028835-A1 | BENZAMIDE COMPOUNDS AS APO B SECRETION INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-04-11 | — | — | WO | disclosed |