Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRNP | P04156 | 1/20 | 0.53 |
| ▸ | PPARG | P37231 | 1/20 | 0.53 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.53 |
| ▸ | NR2E3 | Q9Y5X4 | 1/20 | 0.53 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | GAA | P10253 | 4/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6960129 | 0.86 | SMN1; SMN2 (0.53) | PRNPPPARGRXFP1NR2E3NCOR2 | |
| SCHEMBL6958448 | 0.85 | SMN1; SMN2 (0.69) | PRNPPPARGRXFP1NR2E3NCOR2 | |
| SCHEMBL6955300 | 0.85 | SMN1; SMN2 (0.52) | PRNPPPARGRXFP1NR2E3NCOR2 | |
| SCHEMBL6960507 | 0.85 | PLA2G2A (0.55) | SMN1; SMN2KDM4EALDH1A1GAAMAPT | |
| SCHEMBL16851064 | 0.82 | SMN1; SMN2 (0.72) | SMN1; SMN2KDM4EALDH1A1GAAMAPT | |
| SCHEMBL7083195 | 0.81 | SMN1; SMN2 (0.49) | RXFP1SMN1; SMN2KDM4EALDH1A1GAA | |
| SCHEMBL4384277 | 0.81 | ALDH1A1 (0.64) | SMN1; SMN2KDM4EALDH1A1GAAMAPT | |
| SCHEMBL7076894 | 0.81 | F11 (0.51) | SMN1; SMN2KDM4EALDH1A1GAAMAPT | |
| SCHEMBL6954866 | 0.81 | SMN1; SMN2 (0.51) | SMN1; SMN2KDM4EALDH1A1GAAMAPT | |
| SCHEMBL6956520 | 0.81 | ALDH1A1 (0.64) | SMN1; SMN2KDM4EALDH1A1GAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1023267-B1 | PYRIDYL COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | CERMOL SA (CH) | 2003-09-17 | — | — | EP | claimed |