Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 2/20 | 0.33 |
| ▸ | CA2 | P00918 | 2/20 | 0.32 |
| ▸ | CA4 | P22748 | 2/20 | 0.32 |
| ▸ | SLC6A9 | P48067 | 4/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | VCP | P55072 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7083663 | 0.90 | — | — | |
| SCHEMBL6960600 | 0.88 | ALOX12 (0.36) | SLC6A9 | |
| SCHEMBL6971298 | 0.88 | MAOA (0.34) | CA2CA4SLC6A9VCP | |
| SCHEMBL6961644 | 0.87 | ACSS2 (0.34) | — | |
| SCHEMBL7086504 | 0.87 | GRIN1 (0.33) | — | |
| SCHEMBL6969383 | 0.86 | DHODH (0.41) | DHODHCA2CA4SLC6A9 | |
| SCHEMBL6970022 | 0.85 | CYP2C9 (0.36) | — | |
| SCHEMBL7081196 | 0.84 | DHODH (0.35) | DHODHSLC6A9MAPK1VCP | |
| SCHEMBL7086265 | 0.84 | CA2 (0.36) | DHODHCA2CA4SLC6A9 | |
| SCHEMBL7081810 | 0.83 | CA2 (0.38) | DHODHCA2CA4SLC6A9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0786455-B1 | IMIDAZOLE DERIVATIVE | SHIONOGI & CO (JP) | 2003-12-03 | — | — | EP | disclosed |
| US-6147097-A | METHOD FOR TREATING AIDS | SHIONOGI & CO., LTD. (JP) | 2000-11-14 | — | — | US | disclosed |
| US-5910506-A | IMIDAZOLE DERIVATIVES, E.G.5-(3,5-DICHLOROPHENYLTHIO)-1,2-DIMETHYL-4-ISOPROPYL-1H-IMIDAZOLE; VIRICIDES; AIDS; NONTOXIC | SHIONOGI & CO., LTD. (JP) | 1999-06-08 | — | — | US | disclosed |
| EP-0786455-A1 | IMIDAZOLE DERIVATIVE | SHIONOGI & CO., LTD. (JP) | 1997-07-30 | — | — | EP | disclosed |