Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRSS1 | P07477 | 3/20 | 0.56 |
| ▸ | PRSS2 | P07478 | 3/20 | 0.56 |
| ▸ | PRSS3 | P35030 | 3/20 | 0.56 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.51 |
| ▸ | F10 | P00742 | 3/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | GLA | P06280 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.48 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.48 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.48 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.48 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.48 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7089328 | 0.84 | PRSS1 (0.61) | PRSS1PRSS2PRSS3LOXL2F10 | |
| SCHEMBL28986105 | 0.83 | NPC1 (0.61) | TSHRGAANPC1ALDH1A1GLA | |
| SCHEMBL27589166 | 0.81 | PRSS1 (0.46) | PRSS1PRSS2PRSS3LOXL2F10 | |
| Carbamic Acid SCHEMBL6468271 | 0.81 | NPC1 (0.62) | TSHRGAANPC1ALDH1A1GLA | |
| SCHEMBL14662383 | 0.81 | PRSS1 (0.57) | PRSS1PRSS2PRSS3LOXL2F10 | |
| SCHEMBL7083845 | 0.79 | MEN1 (0.56) | PRSS1PRSS2PRSS3LOXL2F10 | |
| SCHEMBL9226512 | 0.79 | MEP1B (0.51) | TSHRGAANPC1ALDH1A1GLA | |
| SCHEMBL1927016 | 0.79 | ALDH1A1 (0.69) | TSHRGAANPC1ALDH1A1GLA | |
| SCHEMBL6981412 | 0.78 | PTPN1 (0.53) | PRSS1PRSS2PRSS3LOXL2F10 | |
| SCHEMBL7090549 | 0.77 | GRIN2D (0.57) | PRSS1PRSS2PRSS3LOXL2F10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030199698-A1 | Carbamic acid esters as inhibitors of factor xa | MERCK PATENT GMBH (DE) | 2003-10-23 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030199698-A1 | Carbamic acid esters as inhibitors of factor xa | F11, F12, F13A1 | PRSS1 102/4885PRSS2 295/4885PRSS3 628/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.