Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP4K4 | O95819 | 1/20 | 0.45 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.44 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.44 |
| ▸ | USP7 | Q93009 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | METAP2 | P50579 | 1/20 | 0.39 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.38 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.38 |
| ▸ | BACE1 | P56817 | 2/20 | 0.37 |
| ▸ | BACE2 | Q9Y5Z0 | 1/20 | 0.37 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.37 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.37 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.37 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.37 |
| ▸ | CDC42BPB | Q9Y5S2 | 1/20 | 0.37 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.37 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.36 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7133798 | 0.98 | MAP4K4 (0.44) | MAP4K4CYP11B1CYP11B2USP7CYP1A2 | |
| Hydrochloric Acid SCHEMBL7085454 | 0.98 | MAP4K4 (0.44) | MAP4K4CYP11B1CYP11B2USP7CYP1A2 | |
| SCHEMBL17591649 | 0.84 | USP7 (0.44) | MAP4K4CYP11B1CYP11B2USP7CYP1A2 | |
| SCHEMBL17407885 | 0.81 | CYP1A2 (0.55) | MAP4K4CYP11B1CYP11B2USP7CYP1A2 | |
| SCHEMBL30725703 | 0.80 | CYP11B2 (0.57) | MAP4K4CYP11B1CYP11B2USP7IRAK4 | |
| SCHEMBL21044264 | 0.80 | CYP11B2 (0.57) | MAP4K4CYP11B1CYP11B2USP7IRAK4 | |
| SCHEMBL7085557 | 0.79 | MEN1 (0.40) | MAP4K4CYP11B1CYP11B2IRAK4ROCK2 | |
| Hydrochloric Acid SCHEMBL6574831 | 0.76 | MMP3 (0.39) | MAP4K4CYP11B2 | |
| Hydrochloric Acid SCHEMBL6574813 | 0.75 | ADRA2C (0.51) | MAP4K4USP7IRAK4LRRK2ADORA1 | |
| SCHEMBL7091233 | 0.75 | IDO1 (0.42) | CYP11B1CYP11B2BACE1BACE2PRMT5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1052252-B1 | Diaminobenzene derivatives and dyeing preparations containing them | WELLA AG (DE) | 2003-08-06 | — | — | EP | claimed |
| US-6461388-B1 | Diaminobenzene derivative compounds and dye compositions containing same | WELLA AKTIENGESELLSCHAFT (DE) | 2002-10-08 | — | — | US | claimed |
| EP-1052252-A1 | Diaminobenzene derivatives and dyeing preparations containing them | Wella Aktiengesellschaft (DE) | 2000-11-15 | — | — | EP | claimed |
| EP-1052252-B1 | Diaminobenzene derivatives and dyeing preparations containing them | WELLA AG (DE) | 2003-08-06 | — | — | EP | disclosed |
| US-6461388-B1 | Diaminobenzene derivative compounds and dye compositions containing same | WELLA AKTIENGESELLSCHAFT (DE) | 2002-10-08 | — | — | US | disclosed |
| EP-1052252-A1 | Diaminobenzene derivatives and dyeing preparations containing them | Wella Aktiengesellschaft (DE) | 2000-11-15 | — | — | EP | disclosed |