Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 4/20 | 0.53 |
| ▸ | ASH1L | Q9NR48 | 2/20 | 0.51 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.49 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.49 |
| ▸ | PIK3CB | P42338 | 3/20 | 0.47 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.46 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.41 |
| ▸ | AHR | P35869 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | PARP1 | P09874 | 1/20 | 0.40 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
| ▸ | HTR7 | P34969 | 1/20 | 0.40 |
| ▸ | PIP4K2A | P48426 | 1/20 | 0.40 |
| ▸ | PIP4K2B | P78356 | 1/20 | 0.40 |
| ▸ | PIP4K2C | Q8TBX8 | 1/20 | 0.40 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.40 |
| ▸ | HPGDS | O60760 | 1/20 | 0.39 |
| ▸ | ABL1 | P00519 | 1/20 | 0.39 |
| ▸ | BCR | P11274 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31729863 | 0.90 | ASH1L (0.49) | PIK3CDASH1LCSNK2BCSNK2A1PIK3CB | |
| SCHEMBL6321122 | 0.89 | ASH1L (0.55) | PIK3CDASH1LCSNK2BCSNK2A1PIK3CB | |
| SCHEMBL7090984 | 0.85 | PIK3CD (0.63) | PIK3CDASH1LCSNK2BCSNK2A1PIK3CB | |
| SCHEMBL6322590 | 0.78 | PIK3CD (0.57) | PIK3CDASH1LCSNK2BCSNK2A1PIK3CB | |
| SCHEMBL10945814 | 0.77 | PIK3CD (0.75) | PIK3CDASH1LCSNK2BCSNK2A1PIK3CB | |
| SCHEMBL4795341 | 0.76 | PIP4K2A (0.58) | ASH1LPIP4K2APIP4K2BPIP4K2CHPGDS | |
| SCHEMBL15245132 | 0.75 | METAP2 (0.60) | PIK3CDASH1LPIK3CBPIM1GSK3B | |
| SCHEMBL27454514 | 0.75 | PIK3CD (0.57) | PIK3CDASH1LCSNK2BCSNK2A1PIK3CB | |
| SCHEMBL20540332 | 0.74 | PIK3CD (0.64) | PIK3CDASH1LCSNK2BCSNK2A1PIK3CB | |
| SCHEMBL6322388 | 0.73 | ASH1L (0.59) | PIK3CDASH1LCSNK2BCSNK2A1PIK3CB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030203959-A1 | Novel modulators of potassium channels | 4SC AG (DE) | 2003-10-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030203959-A1 | Novel modulators of potassium channels | HCN3, KCNN3, KCNN1 | PIK3CD 3331/4885ASH1L 3744/4885CSNK2B 835/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.