Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 3/20 | 0.63 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.48 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.47 |
| ▸ | ASH1L | Q9NR48 | 2/20 | 0.47 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.46 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.46 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.43 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.43 |
| ▸ | GOT1 | P17174 | 1/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.42 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.42 |
| ▸ | HPGDS | O60760 | 1/20 | 0.42 |
| ▸ | AHR | P35869 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | KIF11 | P52732 | 1/20 | 0.41 |
| ▸ | PIP4K2A | P48426 | 1/20 | 0.40 |
| ▸ | PIP4K2B | P78356 | 1/20 | 0.40 |
| ▸ | PIP4K2C | Q8TBX8 | 1/20 | 0.40 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.40 |
| ▸ | CTSL | P07711 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7085372 | 0.85 | PIK3CD (0.53) | PIK3CDPIK3CBPIK3CGASH1LCSNK2B | |
| SCHEMBL6321122 | 0.84 | ASH1L (0.55) | PIK3CDPIK3CBPIK3CGASH1LCSNK2B | |
| SCHEMBL7088345 | 0.83 | PIK3CD (0.58) | PIK3CDPIK3CBPIK3CGASH1LCSNK2B | |
| SCHEMBL10945814 | 0.82 | PIK3CD (0.75) | PIK3CDPIK3CBPIK3CGASH1LCDK5 | |
| SCHEMBL6322152 | 0.81 | PIK3CD (0.64) | PIK3CDPIK3CBPIK3CGASH1LCDK5 | |
| SCHEMBL6324176 | 0.80 | ABL1 (0.56) | PIK3CDPIK3CBPIK3CGASH1LCSNK2B | |
| SCHEMBL31729863 | 0.79 | ASH1L (0.49) | PIK3CDPIK3CBPIK3CGASH1LCDK5 | |
| SCHEMBL27725234 | 0.79 | PIK3CD (0.66) | PIK3CDPIK3CBPIK3CGASH1LCDK5 | |
| SCHEMBL29712113 | 0.78 | PIK3CD (0.70) | PIK3CDPIK3CBPIK3CGASH1LCDK5 | |
| SCHEMBL2193011 | 0.78 | PIK3CD (0.70) | PIK3CDPIK3CBPIK3CGASH1LCDK5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030203959-A1 | Novel modulators of potassium channels | 4SC AG (DE) | 2003-10-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030203959-A1 | Novel modulators of potassium channels | HCN3, KCNN3, KCNN1 | PIK3CD 3331/4885PIK3CB 3767/4885PIK3CG 3655/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.