SCHEMBL7085408

SCHEMBL7085408

CC1=CC([Zr](Cl)(Cl)C2C=C(C)c3ccccc32)c2ccccc21

nearest known ligand 0.33

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
GPR3 P46089 1/20 0.33
SLC22A2 O15244 1/20 0.31
SLC22A3 O75751 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6554043 0.89 GPR3 (0.33) GPR3SLC22A2SLC22A3
SCHEMBL4268439 0.76 MAPK1 (0.31)
SCHEMBL8857693 0.76 GPR3 (0.31) GPR3
SCHEMBL2805344 0.73 HTR6 (0.33) SLC22A2SLC22A3
SCHEMBL23528115 0.71 HTR6 (0.35)
SCHEMBL6062011 0.71 HTR6 (0.35)
SCHEMBL7272264 0.70 PNMT (0.35)
SCHEMBL5356718 0.70 GPR3 (0.38) GPR3SLC22A2SLC22A3
SCHEMBL29385315 0.70 GPR3 (0.38) GPR3SLC22A2SLC22A3
SCHEMBL6908396 0.69 GPR3 (0.31) GPR3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20140256997-A1 1-OCTENE, 1-DECENE, 1-DODECENE TERNARY COPOLYMER AND LUBRICANT COMPOSITION CONTAINING SAME IDEMITSU KOSAN CO., LTD. (JP) 2014-09-11 US disclosed
EP-0802206-B1 Process and catalyst for producing polyolefins having low molecular weight FINA TECHNOLOGY (US) 2003-07-16 EP disclosed
US-6376418-B1 COORDINATION CATALYSTS FINA TECHNOLOGY, INC. 2002-04-23 US disclosed
US-6114480-A CATALYST COMPRISES A METALLOCENE COMPOUND; PRODUCES CRYSTALLINE OR ATACTIC POLYMER WITH A LOW MOLECULAR WEIGHT AND NARROW OR BROAD MOLECULAR WEIGHT DISTRIBUTION FINA TECHNOLOGY, INC. (US) 2000-09-05 US disclosed
EP-0802206-A2 Process and catalyst for producing polyolefins having low molecular weight FINA TECHNOLOGY, INC. (US) 1997-10-22 EP disclosed