SCHEMBL6554043

SCHEMBL6554043

CC1=CC([Zr](Cl)(Cl)C2c3ccccc3-c3ccccc32)c2ccccc21

nearest known ligand 0.33

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
GPR3 P46089 1/20 0.33
SLC22A2 O15244 1/20 0.31
SLC22A3 O75751 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7085408 0.89 GPR3 (0.33) GPR3SLC22A2SLC22A3
SCHEMBL796784 0.77 GPR3 (0.41) GPR3SLC22A2SLC22A3
SCHEMBL27497067 0.71 GPR3 (0.32) GPR3SLC22A2SLC22A3
SCHEMBL20528871 0.69
SCHEMBL795334 0.69 HTR6 (0.32)
SCHEMBL6547416 0.68 GPR3 (0.41) GPR3SLC22A2SLC22A3
SCHEMBL6553651 0.68 GPR3 (0.32) GPR3SLC22A2SLC22A3
SCHEMBL27389231 0.67 GPR3 (0.41) GPR3SLC22A2SLC22A3
SCHEMBL3679644 0.67
SCHEMBL4268439 0.67 MAPK1 (0.31)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1077215-B1 Asymmetric silicon-bridged metallocenes useful as catalysts in the polymerization of a-olefins, process for their preparation and use of said metallocenes for the polymerization of a-olefins SOLVAY (BE) 2004-02-18 EP disclosed
US-6355747-B1 FOR POLYMERIZATION OF PROPYLENE TO PRODUCE ISOTACTIC POLYPROPYLENE SOLVAY POLYOLEFINS EUROPE-BELGIUM (BE) 2002-03-12 US disclosed
EP-1077215-A1 Asymmetric silicon-bridged metallocenes useful as catalysts in the polymerization of a-olefins, process for their preparation and use of said metallocenes for the polymerization of a-olefins SOLVAY POLYOLEFINS EUROPE - BELGIUM (Société Anonyme) (BE) 2001-02-21 EP disclosed
EP-0754698-A2 An olefin polymerization catalyst and a process for preparing olefin polymer MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1997-01-22 EP disclosed