Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MKNK2 | Q9HBH9 | 4/20 | 0.50 |
| ▸ | MKNK1 | Q9BUB5 | 3/20 | 0.50 |
| ▸ | AXL | P30530 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | PSIP1 | O75475 | 1/20 | 0.50 |
| ▸ | DYRK1A | Q13627 | 3/20 | 0.47 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.47 |
| ▸ | JAK2 | O60674 | 1/20 | 0.47 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.47 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.47 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.47 |
| ▸ | CDK1 | P06493 | 1/20 | 0.47 |
| ▸ | PIM1 | P11309 | 1/20 | 0.47 |
| ▸ | CDK2 | P24941 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | AKT2 | P31751 | 1/20 | 0.47 |
| ▸ | FLT4 | P35916 | 1/20 | 0.47 |
| ▸ | CDK8 | P49336 | 1/20 | 0.47 |
| ▸ | CLK2 | P49760 | 1/20 | 0.47 |
| ▸ | GSK3B | P49841 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7085071 | 0.85 | PRKCD (0.42) | DYRK1AJAK2ROCK2MAP4K4PIM1 | |
| SCHEMBL6570922 | 0.85 | PTGDR2 (0.44) | MAP4K4MAPK1MINK1CLK4ALDH1A1 | |
| Hydrochloric Acid SCHEMBL6573152 | 0.84 | PTGDR2 (0.43) | MAP4K4MAPK1MINK1CLK4ALDH1A1 | |
| SCHEMBL6574148 | 0.84 | KDM4E (0.41) | MAP4K4ALDH1A1MAPTCYP3A4FYN | |
| SCHEMBL6571957 | 0.82 | PRSS1 (0.38) | ALDH1A1HTTCYP3A4 | |
| SCHEMBL6571430 | 0.81 | PRSS1 (0.37) | JAK2AURKBALDH1A1 | |
| SCHEMBL6570749 | 0.79 | PIK3CG (0.41) | MKNK2DYRK1AROCK2MAP4K4PIM1 | |
| SCHEMBL6571342 | 0.78 | USP7 (0.40) | DYRK1AALDH1A1HPGDMAPTDYRK1B | |
| SCHEMBL6570636 | 0.78 | TAAR1 (0.45) | CDK2GSK3BMAPTFYN | |
| SCHEMBL6573384 | 0.78 | ADORA1 (0.51) | CDK5STK3ALDH1A1TDO2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1052252-B1 | Diaminobenzene derivatives and dyeing preparations containing them | WELLA AG (DE) | 2003-08-06 | — | — | EP | claimed |
| US-6461388-B1 | Diaminobenzene derivative compounds and dye compositions containing same | WELLA AKTIENGESELLSCHAFT (DE) | 2002-10-08 | — | — | US | claimed |
| EP-1052252-A1 | Diaminobenzene derivatives and dyeing preparations containing them | Wella Aktiengesellschaft (DE) | 2000-11-15 | — | — | EP | claimed |
| EP-1052252-B1 | Diaminobenzene derivatives and dyeing preparations containing them | WELLA AG (DE) | 2003-08-06 | — | — | EP | disclosed |
| US-6461388-B1 | Diaminobenzene derivative compounds and dye compositions containing same | WELLA AKTIENGESELLSCHAFT (DE) | 2002-10-08 | — | — | US | disclosed |
| EP-1052252-A1 | Diaminobenzene derivatives and dyeing preparations containing them | Wella Aktiengesellschaft (DE) | 2000-11-15 | — | — | EP | disclosed |