SCHEMBL6570636

SCHEMBL6570636

Nc1ccc(NCCO)c(-c2cccc(F)c2)c1

nearest known ligand 0.45

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 3/20 0.45
QPCT Q16769 2/20 0.40
FYN P06241 1/20 0.40
CHRM3 P20309 3/20 0.39
SRC P12931 1/20 0.37
VSIR Q9H7M9 2/20 0.36
POLB P06746 1/20 0.36
MAPT P10636 1/20 0.36
GSK3A P49840 1/20 0.36
GSK3B P49841 1/20 0.36
ADORA1 P30542 2/20 0.36
EGFR P00533 1/20 0.36
CCNA2 P20248 1/20 0.36
CDK2 P24941 1/20 0.36
SLC22A12 Q96S37 1/20 0.35
ESR2 Q92731 2/20 0.35
ESR1 P03372 1/20 0.35
ESRRG P62508 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6574148 0.90 KDM4E (0.41) FYNCHRM3MAPTADORA1
SCHEMBL6571157 0.85 TDO2 (0.38) QPCTCHRM3
SCHEMBL6570922 0.85 PTGDR2 (0.44) POLBADORA1
SCHEMBL6570749 0.84 PIK3CG (0.41) SRCMAPTADORA1
Hydrochloric Acid SCHEMBL6573152 0.84 PTGDR2 (0.43) ADORA1
SCHEMBL6573384 0.83 ADORA1 (0.51) TAAR1SRCMAPTADORA1
SCHEMBL6570923 0.83 MAPT (0.37) TAAR1POLBMAPTADORA1EGFR
SCHEMBL6571506 0.83 RORC (0.47) FYNADORA1
SCHEMBL6571957 0.82 PRSS1 (0.38)
SCHEMBL6572463 0.82 ALDH1A1 (0.46) FYNCHRM3POLBMAPTADORA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1051143-B1 OXIDIZING HAIR COLORING AGENTS CONTAINING 2,5-DIAMINO-1-PHENYLBENZENE DERIVATIVES AND NOVEL 2,5-DIAMINO-1-PHENYLBENZENE DERIVATIVES WELLA AG (DE) 2004-07-21 EP claimed
EP-1051143-B1 OXIDIZING HAIR COLORING AGENTS CONTAINING 2,5-DIAMINO-1-PHENYLBENZENE DERIVATIVES AND NOVEL 2,5-DIAMINO-1-PHENYLBENZENE DERIVATIVES WELLA AG (DE) 2004-07-21 EP disclosed
US-6500213-B1 Oxidizing hair coloring agents containing 2,5-diamino-1-phenylbenzene derivatives and novel 2,5-diamino-1-phenylbenzene derivatives WELLA AKTIENGESELLSCHAFT (DE) 2002-12-31 US disclosed
EP-1051143-A2 OXIDIZING HAIR COLORING AGENTS CONTAINING 2,5-DIAMINO-1-PHENYLBENZENE DERIVATIVES AND NOVEL 2,5-DIAMINO-1-PHENYLBENZENE DERIVATIVES Wella Aktiengesellschaft (DE) 2000-11-15 EP disclosed
WO-1999059527-A2 OXIDIZING HAIR COLORING AGENTS CONTAINING 2,5-DIAMINO-1-PHENYLBENZENE DERIVATIVES AND NOVEL 2,5-DIAMINO-1-PHENYLBENZENE DERIVATIVES WELLA AKTIENGESELLSCHAFT (DE) 1999-11-25 WO disclosed