Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 2/20 | 0.53 |
| ▸ | CYP1A1 | P04798 | 4/20 | 0.51 |
| ▸ | CYP1B1 | Q16678 | 4/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.51 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.47 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.47 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.47 |
| ▸ | STAT6 | P42226 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.46 |
| ▸ | LCK | P06239 | 2/20 | 0.46 |
| ▸ | CASP3 | P42574 | 1/20 | 0.46 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.46 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | HPGD | P15428 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.46 |
| ▸ | GLA | P06280 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12835493 | 0.93 | CYP2D6 (0.49) | CYP2D6CYP1A1CYP1B1CYP1A2ABCB1 | |
| SCHEMBL12835290 | 0.91 | CYP1A2 (0.59) | CYP2D6CYP1A1CYP1B1CYP1A2ABCB1 | |
| Mitoflaxone SCHEMBL106705 | 0.84 | CYP1A2 (0.62) | CYP2D6CYP1A1CYP1B1CYP1A2ABCB1 | |
| SCHEMBL9526692 | 0.82 | HSD17B10 (0.53) | CYP2D6CYP1A1CYP1B1CYP1A2ABCB1 | |
| SCHEMBL9327677 | 0.82 | CYP2D6 (0.53) | CYP2D6CYP1A1CYP1B1CYP1A2ABCB1 | |
| SCHEMBL12835503 | 0.82 | CYP1A2 (0.60) | CYP2D6CYP1A1CYP1B1CYP1A2ABCB1 | |
| SCHEMBL7083153 | 0.81 | CYP2D6 (0.54) | CYP2D6CYP1A1CYP1B1CYP1A2ABCB1 | |
| SCHEMBL9328729 | 0.81 | CYP2D6 (0.49) | CYP2D6CYP1A1CYP1B1CYP1A2ABCB1 | |
| SCHEMBL12835338 | 0.81 | TDP1 (0.57) | CYP2D6CYP1A1CYP1B1CYP1A2CYP3A4 | |
| SCHEMBL12835507 | 0.81 | ALDH1A1 (0.70) | CYP2D6CYP1A1CYP1B1CYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1328262-A2 | A METHOD TO INCORPORATE N-(4-HYDROXYPHENYL) RETINAMIDE IN LIPOSOMES | Board of Regents, The University of Texas System (US) | 2003-07-23 | — | — | EP | disclosed |
| US-20020143062-A1 | Method to incorporate N-(4-hydroxyphenyl) retinamide in liposomes | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM | 2002-10-03 | — | — | US | disclosed |
| WO-2002032413-A2 | A METHOD TO INCORPORATE N-(4-HYDROXYPHENYL) RETINAMIDE IN LIPOSOMES | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2002-04-25 | — | — | WO | disclosed |
| US-5116954-A | Antitumor agents | LIPHA, LYONNAISE INDUSTRIELLE PHARMACEUTIQUE (FR) | 1992-05-26 | — | — | US | disclosed |