Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 3/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 7/20 | 0.52 |
| ▸ | TP53 | P04637 | 6/20 | 0.52 |
| ▸ | MAPT | P10636 | 6/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 5/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.52 |
| ▸ | HPGD | P15428 | 5/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.51 |
| ▸ | STAT6 | P42226 | 1/20 | 0.51 |
| ▸ | GLA | P06280 | 1/20 | 0.50 |
| ▸ | STING1 | Q86WV6 | 1/20 | 0.50 |
| ▸ | RECQL | P46063 | 2/20 | 0.48 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.47 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.47 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.47 |
| ▸ | CYP1A1 | P04798 | 3/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Mitoflaxone SCHEMBL106705 | 0.89 | CYP1A2 (0.62) | CYP2D6CYP3A4TP53MAPTMAPK1 | |
| SCHEMBL12835503 | 0.86 | CYP1A2 (0.60) | CYP2D6CYP3A4TP53MAPTMAPK1 | |
| SCHEMBL12835531 | 0.85 | CYP1A2 (0.54) | CYP2D6CYP3A4TP53MAPTMAPK1 | |
| SCHEMBL7083117 | 0.85 | CYP1A2 (0.59) | CYP2D6CYP3A4TP53MAPTMAPK1 | |
| SCHEMBL9328614 | 0.85 | CYP1A2 (0.59) | CYP2D6CYP3A4TP53MAPTMAPK1 | |
| SCHEMBL12835493 | 0.84 | CYP2D6 (0.49) | CYP2D6CYP3A4TP53MAPTMAPK1 | |
| SCHEMBL12835629 | 0.83 | CYP2D6 (0.53) | CYP2D6CYP3A4TP53MAPTMAPK1 | |
| SCHEMBL9526792 | 0.83 | NQO2 (0.53) | CYP2D6CYP3A4TP53MAPTMAPK1 | |
| SCHEMBL12835338 | 0.82 | TDP1 (0.57) | CYP2D6CYP3A4TP53MAPTMAPK1 | |
| SCHEMBL7085632 | 0.82 | CYP2D6 (0.53) | CYP2D6CYP3A4TP53MAPTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011023287-A1 | USE OF FAA AND ITS DERIVATIVES IN COSMETICS AND DERMATOLOGY | MERCK PATENT GMBH (DE) | 2011-03-03 | — | — | WO | disclosed |
| EP-1328262-A2 | A METHOD TO INCORPORATE N-(4-HYDROXYPHENYL) RETINAMIDE IN LIPOSOMES | Board of Regents, The University of Texas System (US) | 2003-07-23 | — | — | EP | disclosed |
| US-20020143062-A1 | Method to incorporate N-(4-hydroxyphenyl) retinamide in liposomes | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM | 2002-10-03 | — | — | US | disclosed |
| WO-2002032413-A2 | A METHOD TO INCORPORATE N-(4-HYDROXYPHENYL) RETINAMIDE IN LIPOSOMES | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2002-04-25 | — | — | WO | disclosed |
| EP-0341104-B1 | Substituted flavonoid compounds, their salts, their manufacture and medicines containing these materials | MERCK PATENT GMBH (DE) | 1993-12-29 | — | — | EP | disclosed |
| US-5116954-A | Antitumor agents | LIPHA, LYONNAISE INDUSTRIELLE PHARMACEUTIQUE (FR) | 1992-05-26 | — | — | US | disclosed |
| EP-0341104-A2 | Substituted flavonoid compounds, their salts, their manufacture and medicines containing these materials | MERCK PATENT GmbH (DE) | 1989-11-08 | — | — | EP | disclosed |