Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 1/20 | 0.55 |
| ▸ | TAS2R14 | Q9NYV8 | 5/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3196609 | 0.84 | NPC1 (0.51) | MEN1KMT2AMAPTALDH1A1POLB | |
| SCHEMBL17784998 | 0.81 | TSHR (0.57) | CA2MEN1KMT2AALDH1A1GAA | |
| SCHEMBL15212712 | 0.77 | CA2 (0.55) | CA2TAS2R14MEN1KMT2AMAPT | |
| SCHEMBL673366 | 0.74 | CA2 (0.68) | CA2TAS2R14MEN1KMT2AMAPT | |
| SCHEMBL7082389 | 0.74 | MMP3 (0.50) | CA2MEN1KMT2AALDH1A1NPC1 | |
| Ethane SCHEMBL23927829 | 0.72 | CA2 (0.59) | CA2TAS2R14MEN1KMT2AMAPT | |
| SCHEMBL5772823 | 0.72 | ESR1 (0.44) | KMT2AALDH1A1POLBHTTNPC1 | |
| SCHEMBL9492107 | 0.72 | CA1 (0.64) | CA2KMT2AALDH1A1 | |
| SCHEMBL6421016 | 0.72 | CA2 (0.53) | CA2TAS2R14MEN1KMT2AMAPT | |
| SCHEMBL10312253 | 0.71 | ALDH1A1 (0.64) | CA2ALDH1A1POLBSMN1; SMN2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0592439-B1 | AMINOSULFONYL CARBAMATES | WARNER LAMBERT CO (US) | 2003-07-30 | — | — | EP | claimed |