SCHEMBL7082389

SCHEMBL7082389

CN(CCc1ccccc1)S(=O)(=O)NC(=O)O

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MMP3 P08254 2/20 0.50
TAAR1 Q96RJ0 1/20 0.47
HDAC3 O15379 1/20 0.45
HDAC4 P56524 1/20 0.45
HDAC1 Q13547 1/20 0.45
HDAC7 Q8WUI4 1/20 0.45
HDAC2 Q92769 1/20 0.45
HDAC8 Q9BY41 1/20 0.45
HDAC6 Q9UBN7 1/20 0.45
HDAC9 Q9UKV0 1/20 0.45
HDAC5 Q9UQL6 1/20 0.45
AOC3 Q16853 1/20 0.44
CA12 O43570 1/20 0.43
CA1 P00915 1/20 0.43
CA2 P00918 1/20 0.43
CA9 Q16790 1/20 0.43
NPY5R Q15761 1/20 0.43
TDP1 Q9NUW8 2/20 0.42
KMT2A Q03164 2/20 0.42
NPC1 O15118 2/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3196609 0.83 NPC1 (0.51) MMP3CA12CA9KMT2ANPC1
SCHEMBL25477196 0.78 TAAR1 (0.55) MMP3TAAR1HDAC3HDAC4HDAC1
SCHEMBL8984905 0.77
SCHEMBL13184564 0.75 TAAR1 (0.57) MMP3TAAR1AOC3TSHRCNR2
SCHEMBL1646282 0.74 AOC3 (0.57) MMP3TAAR1AOC3CA12CA1
SCHEMBL6335172 0.74 TAAR1 (0.55) MMP3TAAR1HDAC3HDAC4HDAC1
SCHEMBL7085689 0.74 CA2 (0.55) CA2KMT2ANPC1RAB9AMEN1
SCHEMBL7309475 0.74 MMP3 (0.60) MMP3TAAR1HDAC3HDAC4HDAC1
SCHEMBL15135141 0.73 ALDH1A1 (0.36) CA1CA2KMT2AMEN1ALDH1A1
SCHEMBL7302947 0.73 MMP3 (0.59) MMP3TAAR1HDAC3HDAC4HDAC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0592439-B1 AMINOSULFONYL CARBAMATES WARNER LAMBERT CO (US) 2003-07-30 EP claimed