Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 4/20 | 0.37 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.35 |
| ▸ | POLB | P06746 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7088752 | 0.81 | HSD17B10 (0.38) | HSD17B10HPGDADORA2BMAPK1TDP1 | |
| SCHEMBL7087213 | 0.78 | AKR1B1 (0.37) | HSD17B10HPGDTDP1MAPTKMT2A | |
| SCHEMBL7086096 | 0.77 | HPGD (0.41) | HSD17B10HPGDTDP1MAPTKMT2A | |
| SCHEMBL7089716 | 0.75 | AKR1B1 (0.34) | HPGDTDP1MAPTDUSP3PTPN5 | |
| SCHEMBL7083182 | 0.73 | PTGDR2 (0.33) | TDP1MAPTGAAKDM4ECYP1A2 | |
| SCHEMBL7086053 | 0.71 | L3MBTL1 (0.36) | HSD17B10HPGDTDP1POLBMAPT | |
| SCHEMBL4649113 | 0.69 | AKR1B1 (0.50) | TDP1POLBMAPTKMT2AL3MBTL1 | |
| SCHEMBL11701645 | 0.66 | BRD4 (0.44) | TDP1AKR1B1 | |
| SCHEMBL7081707 | 0.62 | AKR1B1 (0.37) | HPGDTDP1CYP2C9CYP2C19DUSP3 | |
| SCHEMBL7082800 | 0.62 | AKR1B1 (0.37) | TDP1DUSP3PTPN5PTPN11CTDSP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1328262-A2 | A METHOD TO INCORPORATE N-(4-HYDROXYPHENYL) RETINAMIDE IN LIPOSOMES | Board of Regents, The University of Texas System (US) | 2003-07-23 | — | — | EP | disclosed |
| WO-2002032413-A2 | A METHOD TO INCORPORATE N-(4-HYDROXYPHENYL) RETINAMIDE IN LIPOSOMES | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2002-04-25 | — | — | WO | disclosed |