Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1B1 | P15121 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.36 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.36 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.36 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.36 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.35 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.35 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.35 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.35 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.35 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.35 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 4/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | STING1 | Q86WV6 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7089716 | 0.80 | AKR1B1 (0.34) | AKR1B1TDP1DUSP3PTPN5PTPN11 | |
| SCHEMBL7083182 | 0.78 | PTGDR2 (0.33) | AKR1B1TDP1DUSP3PTPN5PTPN11 | |
| SCHEMBL7085894 | 0.78 | HSD17B10 (0.38) | AKR1B1TDP1DUSP3PTPN5PTPN11 | |
| SCHEMBL7156303 | 0.78 | HPGD (0.35) | TDP1HPGDALDH1A1MEN1MAPT | |
| SCHEMBL7086053 | 0.75 | L3MBTL1 (0.36) | TDP1HPGDALDH1A1MEN1MAPT | |
| SCHEMBL7086096 | 0.74 | HPGD (0.41) | TDP1HPGDALDH1A1MEN1MAPT | |
| SCHEMBL13620480 | 0.74 | HPGD (0.50) | TDP1HPGDALDH1A1MEN1MAPT | |
| SCHEMBL28940452 | 0.71 | MAPT (0.47) | HPGDALDH1A1MEN1MAPTKMT2A | |
| SCHEMBL7087461 | 0.67 | EDNRA (0.35) | AKR1B1TDP1DUSP3PTPN5PTPN11 | |
| SCHEMBL7082800 | 0.67 | AKR1B1 (0.37) | AKR1B1TDP1DUSP3PTPN5PTPN11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1328262-A2 | A METHOD TO INCORPORATE N-(4-HYDROXYPHENYL) RETINAMIDE IN LIPOSOMES | Board of Regents, The University of Texas System (US) | 2003-07-23 | — | — | EP | disclosed |
| WO-2002032413-A2 | A METHOD TO INCORPORATE N-(4-HYDROXYPHENYL) RETINAMIDE IN LIPOSOMES | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2002-04-25 | — | — | WO | disclosed |