Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | CRHBP | P24387 | 1/20 | 0.36 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.36 |
| ▸ | MMP13 | P45452 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7088729 | 0.82 | HPGD (0.41) | HPGDALDH1A1GAAHSD17B10MAPT | |
| SCHEMBL7085894 | 0.77 | HSD17B10 (0.38) | HPGDALDH1A1GAAHSD17B10MAPT | |
| SCHEMBL7087213 | 0.74 | AKR1B1 (0.37) | HPGDALDH1A1GAAHSD17B10MAPT | |
| SCHEMBL7089716 | 0.72 | AKR1B1 (0.34) | HPGDMAPTTDP1 | |
| SCHEMBL11492038 | 0.72 | KMT2A (0.67) | HPGDALDH1A1GAAHSD17B10MAPT | |
| SCHEMBL7083182 | 0.70 | PTGDR2 (0.33) | GAAMAPTTDP1 | |
| SCHEMBL880298 | 0.69 | ALDH1A1 (0.51) | HPGDALDH1A1GAAHSD17B10MAPT | |
| SCHEMBL11701645 | 0.68 | BRD4 (0.44) | TDP1 | |
| SCHEMBL7086053 | 0.67 | L3MBTL1 (0.36) | HPGDALDH1A1HSD17B10MAPTMEN1 | |
| SCHEMBL880286 | 0.66 | MAPT (0.56) | HPGDALDH1A1GAAHSD17B10MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1328262-A2 | A METHOD TO INCORPORATE N-(4-HYDROXYPHENYL) RETINAMIDE IN LIPOSOMES | Board of Regents, The University of Texas System (US) | 2003-07-23 | — | — | EP | disclosed |
| WO-2002032413-A2 | A METHOD TO INCORPORATE N-(4-HYDROXYPHENYL) RETINAMIDE IN LIPOSOMES | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2002-04-25 | — | — | WO | disclosed |