Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 5/20 | 0.40 |
| ▸ | RAB9A | P51151 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.39 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.39 |
| ▸ | ITGAV | P06756 | 1/20 | 0.39 |
| ▸ | ITGA5 | P08648 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | PABPC1 | P11940 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.37 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6796448 | 0.90 | LMNA (0.43) | CYP1A2GAANPC1RAB9AMEN1 | |
| SCHEMBL6487610 | 0.87 | MAPT (0.48) | CYP1A2GAANPC1RAB9AMEN1 | |
| SCHEMBL6500770 | 0.84 | ITGB3 (0.41) | ITGB3ITGB1ITGAVITGA5 | |
| SCHEMBL6488833 | 0.82 | SIRT1 (0.40) | CYP1A2GAANPC1RAB9AMEN1 | |
| SCHEMBL6497053 | 0.79 | NPC1 (0.46) | NPC1RAB9AMEN1KMT2AMAPT | |
| SCHEMBL7086795 | 0.79 | CYP2C19 (0.40) | CYP1A2GAANPC1RAB9AMEN1 | |
| SCHEMBL10233481 | 0.77 | CA12 (0.48) | CYP1A2GAANPC1RAB9AMEN1 | |
| SCHEMBL115820 | 0.76 | CYP1A2 (0.65) | CYP1A2GAANPC1RAB9AMEN1 | |
| SCHEMBL6500907 | 0.76 | MMP1 (0.39) | NPC1RAB9AMEN1KMT2AMAPT | |
| SCHEMBL16980508 | 0.76 | CA12 (0.49) | CYP1A2GAARAB9AMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1326835-A1 | BENZAMIDE COMPOUNDS AS APO B SECRETION INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2003-07-16 | — | — | EP | disclosed |
| WO-2002028835-A1 | BENZAMIDE COMPOUNDS AS APO B SECRETION INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-04-11 | — | — | WO | disclosed |