Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | POLB | P06746 | 3/20 | 0.42 |
| ▸ | KEAP1 | Q14145 | 3/20 | 0.41 |
| ▸ | NFE2L2 | Q16236 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA7 | P43166 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | GMNN | O75496 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | MMP2 | P08253 | 2/20 | 0.39 |
| ▸ | MMP3 | P08254 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6639307 | 0.80 | LMNA (0.42) | ALDH1A1CA12CA9LMNA | |
| SCHEMBL8984942 | 0.77 | NLRP3 (0.53) | — | |
| SCHEMBL11214430 | 0.76 | HDAC1 (0.62) | HDAC1ALDH1A1POLBKEAP1NFE2L2 | |
| SCHEMBL2392454 | 0.73 | KMT2A (0.43) | ALDH1A1POLBKMT2ANPSR1LMNA | |
| SCHEMBL3217835 | 0.72 | HTT (0.51) | ALDH1A1NPSR1KDM4EMMP2MMP9 | |
| SCHEMBL3202261 | 0.71 | CA14 (0.38) | CA12CA7CA9CA14KDM4E | |
| SCHEMBL10037153 | 0.71 | ALDH1A1 (0.60) | ALDH1A1KMT2ACA12CA7CA9 | |
| SCHEMBL185646 | 0.71 | HDAC1 (0.60) | HDAC1ALDH1A1POLBKMT2ALMNA | |
| SCHEMBL3221517 | 0.70 | CYP2C19 (0.41) | CA12CA7CA9CA14LMNA | |
| SCHEMBL19652080 | 0.69 | POLB (0.60) | HDAC1ALDH1A1POLBKEAP1NFE2L2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0592439-B1 | AMINOSULFONYL CARBAMATES | WARNER LAMBERT CO (US) | 2003-07-30 | — | — | EP | claimed |