Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.51 |
| ▸ | CCR3 | P51677 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.42 |
| ▸ | MMP2 | P08253 | 2/20 | 0.41 |
| ▸ | MMP9 | P14780 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6639307 | 0.76 | LMNA (0.42) | ALDH1A1CYP2D6CYP2C19 | |
| SCHEMBL7568101 | 0.74 | SMN1; SMN2 (0.46) | HTTALDH1A1NCOA1SMN1; SMN2NCOA3 | |
| SCHEMBL30801085 | 0.73 | CA2 (0.63) | ALDH1A1SMN1; SMN2NPSR1L3MBTL1CYP1A2 | |
| SCHEMBL16300320 | 0.73 | CA2 (0.63) | ALDH1A1SMN1; SMN2NPSR1L3MBTL1CYP1A2 | |
| SCHEMBL7086849 | 0.72 | HDAC1 (0.46) | ALDH1A1KDM4ENPSR1MMP2MMP9 | |
| SCHEMBL3221517 | 0.70 | CYP2C19 (0.41) | CYP2C19 | |
| SCHEMBL14350793 | 0.70 | ALDH1A1 (0.66) | HTTALDH1A1NCOA1SMN1; SMN2NCOA3 | |
| SCHEMBL9505332 | 0.70 | ALDH1A1 (0.66) | HTTALDH1A1NCOA1SMN1; SMN2NCOA3 | |
| SCHEMBL13647281 | 0.70 | ALDH1A1 (0.66) | HTTALDH1A1NCOA1SMN1; SMN2NCOA3 | |
| SCHEMBL3511543 | 0.70 | HTT (0.56) | HTTALDH1A1NCOA1SMN1; SMN2NCOA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100041892-A1 | Therapeutic agent for diabetes | ABE HIDENORI | 2010-02-18 | — | — | US | disclosed |
| US-20090270631-A1 | Therapeutic agent for diabetes | ABE HIDENORI | 2009-10-29 | — | — | US | disclosed |
| US-20080009530-A1 | Therapeutic Agent for Diabetes | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2008-01-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090270631-A1 | Therapeutic agent for diabetes | FABP4, SLC5A1, SLC5A2 | HTT 3900/4885ALDH1A1 212/4885NCOA1 338/4885 |
| US-20080009530-A1 | Therapeutic Agent for Diabetes | FABP4, SLC5A1, SLC5A2 | HTT 3997/4885ALDH1A1 118/4885NCOA1 236/4885 |
| US-20100041892-A1 | Therapeutic agent for diabetes | FABP4, SLC5A1, SLC5A2 | HTT 3900/4885ALDH1A1 212/4885NCOA1 338/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.