SCHEMBL7086987

SCHEMBL7086987

CC(C)N(Cc1cccc(C(=N)NO)c1)C(=O)O

nearest known ligand 0.51

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.51
KMT2A Q03164 2/20 0.51
MEP1B Q16820 13/20 0.46
PPARG P37231 1/20 0.46
MEP1A Q16819 3/20 0.45
ATM Q13315 1/20 0.42
PTGES O14684 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7090040 0.89 MEP1B (0.43) MEN1KMT2AMEP1BPPARGMEP1A
SCHEMBL7083824 0.84 PRSS1 (0.51) MEN1KMT2APPARG
SCHEMBL7087183 0.82 MEN1 (0.54) MEN1KMT2AMEP1BMEP1A
SCHEMBL7083364 0.82 GRIN2D (0.51) MEP1BPPARGMEP1APTGES
SCHEMBL7087160 0.81 MEP1B (0.53) MEN1KMT2AMEP1BPPARGMEP1A
SCHEMBL7083688 0.80 PPARG (0.52) KMT2AMEP1BPPARGMEP1A
SCHEMBL7087197 0.78 HDAC1 (0.53) MEP1BPPARGMEP1A
SCHEMBL6448577 0.77 NOS1 (0.44) MEN1KMT2AMEP1BMEP1A
SCHEMBL1701279 0.76 KMT2A (0.76) MEN1KMT2AATM
SCHEMBL7083256 0.76 HDAC1 (0.55) MEP1BPPARGMEP1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20030199698-A1 Carbamic acid esters as inhibitors of factor xa MERCK PATENT GMBH (DE) 2003-10-23 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030199698-A1 Carbamic acid esters as inhibitors of factor xa F11, F12, F13A1 MEN1 513/4885KMT2A 2403/4885MEP1B 139/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.