Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDH1 | O75874 | 18/20 | 0.46 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.43 |
| ▸ | KDM4B | O94953 | 1/20 | 0.43 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.43 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.43 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.43 |
| ▸ | DOHH | Q9BU89 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7087593 | 0.84 | IDH1 (0.44) | IDH1NR1I2KDM4BCHRM1TBXA2R | |
| SCHEMBL11852460 | 0.78 | IDH1 (0.54) | IDH1 | |
| SCHEMBL13827862 | 0.77 | PLA2G7 (0.34) | IDH1 | |
| SCHEMBL10730246 | 0.76 | IDH1 (0.51) | IDH1NR1I2KDM4BCHRM1TBXA2R | |
| SCHEMBL11848025 | 0.75 | NR1I2 (0.55) | IDH1NR1I2KDM4BCHRM1TBXA2R | |
| SCHEMBL10726848 | 0.73 | IDH1 (0.42) | IDH1NR1I2KDM4BCHRM1TBXA2R | |
| SCHEMBL21762069 | 0.73 | IDH1 (0.42) | IDH1NR1I2KDM4BCHRM1TBXA2R | |
| SCHEMBL11435622 | 0.73 | IDH1 (0.49) | IDH1NR1I2KDM4BCHRM1TBXA2R | |
| Metipirox SCHEMBL794955 | 0.73 | IDH1 (0.52) | IDH1NR1I2KDM4BCHRM1TBXA2R | |
| SCHEMBL10724185 | 0.71 | IDH1 (0.47) | IDH1NR1I2KDM4BCHRM1TBXA2R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4185106-A | Pyridones as antidandruff agents | HOECHST AKTIENGESELLSCHAFT (DE) | 1980-01-22 | — | — | US | claimed |
| EP-4626862-A1 | PROCESS FOR THE PREPARATION OF N-HYDROXYPYRIDONE COMPOUNDS | CLARIANT INTERNATIONAL LTD (CH) | 2025-10-08 | — | — | EP | disclosed |
| WO-2024115319-A1 | PROCESS FOR THE PREPARATION OF N-HYDROXYPYRIDONE COMPOUNDS | CLARIANT INTERNATIONAL LTD (CH) | 2024-06-06 | — | — | WO | disclosed |
| US-20030228340-A1 | Methods for treating rosacea with pyridones | MEDICIS PHARMACEUTICAL CORPORATION | 2003-12-11 | — | — | US | disclosed |
| WO-2003084538-A1 | METHODS FOR TREATING ROSACEA WITH PYRIDONES | MEDICIS PHARMACEUTICAL CORPORATION (US) | 2003-10-16 | — | — | WO | disclosed |
| EP-0510440-B1 | Positive-working radiation-sensitive composition and radiation-sensitive recording material produced therewith | CLARIANT GMBH (DE) | 1999-01-13 | — | — | EP | disclosed |
| EP-0510443-B1 | Negative-working radiation-sensitive composition and radiation-sensitive recording material produced therewith | HOECHST AG (DE) | 1995-03-22 | — | — | EP | disclosed |
| US-5230985-A | NEGATIVE-WORKING RADIATION-SENSITIVE MIXTURES, AND RADIATION-SENSITIVE RECORDING MATERIAL PRODUCED WITH THESE MIXTURES | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-07-27 | — | — | US | disclosed |
| US-5229254-A | Photoresists, printing plates, sulfonic acid generators | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-07-20 | — | — | US | disclosed |
| EP-0510443-A1 | Negative-working radiation-sensitive composition and radiation-sensitive recording material produced therewith | HOECHST AKTIENGESELLSCHAFT (DE) | 1992-10-28 | — | — | EP | disclosed |
| EP-0510440-A1 | Positive-working radiation-sensitive composition and radiation-sensitive recording material produced therewith | HOECHST AKTIENGESELLSCHAFT (DE) | 1992-10-28 | — | — | EP | disclosed |
| US-4711775-A | ANTIDANDRUFF HAIR LOTIONS AND SHAMPOOS | HOECHST AKTIENGESELLSCHAFT (DE) | 1987-12-08 | — | — | US | disclosed |
| US-4185106-A | Pyridones as antidandruff agents | HOECHST AKTIENGESELLSCHAFT (DE) | 1980-01-22 | — | — | US | disclosed |
| US-3972888-A | Process for the preparation of 1-hydroxy-pyridones | HOECHST AKTIENGESELLSCHAFT (DT) | 1976-08-03 | — | — | US | disclosed |
| US-3968118-A | Process for the manufacture of 1-hydroxy-2-pyridones | HOECHST AKTIENGESELLSCHAFT (DT) | 1976-07-06 | — | — | US | disclosed |