Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDH1 | O75874 | 18/20 | 0.42 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.36 |
| ▸ | KDM4B | O94953 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.36 |
| ▸ | DOHH | Q9BU89 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10729237 | 0.91 | IDH1 (0.40) | IDH1NR1I2KDM4BCHRM1TBXA2R | |
| SCHEMBL22844949 | 0.75 | IDH1 (0.40) | IDH1 | |
| SCHEMBL7087619 | 0.73 | IDH1 (0.46) | IDH1NR1I2KDM4BCHRM1TBXA2R | |
| SCHEMBL7087593 | 0.70 | IDH1 (0.44) | IDH1NR1I2KDM4BCHRM1TBXA2R | |
| SCHEMBL10937535 | 0.69 | MMP2 (0.46) | IDH1 | |
| SCHEMBL627794 | 0.68 | IDH1 (0.39) | IDH1NR1I2KDM4BCHRM1TBXA2R | |
| SCHEMBL795574 | 0.67 | ALDH1A1 (0.39) | IDH1 | |
| SCHEMBL10730246 | 0.67 | IDH1 (0.51) | IDH1NR1I2KDM4BCHRM1TBXA2R | |
| SCHEMBL7089306 | 0.66 | IDH1 (0.65) | IDH1 | |
| SCHEMBL11852460 | 0.66 | IDH1 (0.54) | IDH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020040327-A1 | USE OF CICLOPIROX FOR INHIBITING HBV CORE ASSEMBLY | 광주과학기술원 | 2020-02-27 | — | — | WO | disclosed |