Metipirox

Metipirox

SCHEMBL794955

Cc1cc(C)n(O)c(=O)c1

nearest known ligand 0.52

Full drug profile on Sugi Atlas →

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
IDH1 O75874 18/20 0.52
NR1I2 O75469 1/20 0.48
KDM4B O94953 1/20 0.48
CHRM1 P11229 1/20 0.48
TBXA2R P21731 1/20 0.48
ADRA1A P35348 1/20 0.48
DOHH Q9BU89 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15287245 0.78 POLB (0.55) IDH1NR1I2KDM4BCHRM1TBXA2R
SCHEMBL7089306 0.73 IDH1 (0.65) IDH1
SCHEMBL7087619 0.73 IDH1 (0.46) IDH1NR1I2KDM4BCHRM1TBXA2R
SCHEMBL8521071 0.72 CYP1A2 (0.44) IDH1NR1I2KDM4BCHRM1TBXA2R
SCHEMBL7091685 0.72 IDH1 (0.62) IDH1
SCHEMBL11822962 0.72 IDH1 (0.62) IDH1
SCHEMBL28952245 0.71 IDH1 (0.82) IDH1
SCHEMBL10726835 0.70 GLO1 (0.65) IDH1
SCHEMBL796299 0.70 GLO1 (0.53) IDH1NR1I2KDM4BCHRM1TBXA2R
SCHEMBL7087597 0.70 IDH1 (0.61) IDH1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 392 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4626862-A1 PROCESS FOR THE PREPARATION OF N-HYDROXYPYRIDONE COMPOUNDS CLARIANT INTERNATIONAL LTD (CH) 2025-10-08 EP claimed
WO-2024115319-A1 PROCESS FOR THE PREPARATION OF N-HYDROXYPYRIDONE COMPOUNDS CLARIANT INTERNATIONAL LTD (CH) 2024-06-06 WO claimed
US-20170088800-A1 DETERGENT COMPOSITIONS CONTAINING PYRIDINOL-N-OXIDE COMPOSITIONS PROCTER & GAMBLE (US) 2017-03-30 US claimed
EP-2744881-B1 DETERGENT COMPOSITIONS CONTAINING PYRIDINOL-N-OXIDE COMPOUNDS PROCTER & GAMBLE (US) 2016-01-20 EP claimed
US-9016221-B2 Surface topographies for non-toxic bioadhesion control UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) 2015-04-28 US claimed
US-8841247-B2 Detergent compositions containing pyridinol-N-oxide compositions THE PROCTER & GAMBLE COMPANY (US) 2014-09-23 US claimed
EP-2744881-A1 DETERGENT COMPOSITIONS CONTAINING PYRIDINOL-N-OXIDE COMPOUNDS The Procter and Gamble Company (US) 2014-06-25 EP claimed
WO-2013025742-A1 DETERGENT COMPOSITIONS CONTAINING PYRIDINOL-N-OXIDE COMPOUNDS THE PROCTER & GAMBLE COMPANY (US) 2013-02-21 WO claimed
US-20130045910-A1 DETERGENT COMPOSITIONS CONTAINING PYRIDINOL-N-OXIDE COMPOSITIONS THE PROCTER & GAMBLE COMPANY 2013-02-21 US claimed
US-20100226943-A1 SURFACE TOPOGRAPHIES FOR NON-TOXIC BIOADHESION CONTROL UNIVERSITY OF FLORIDA (US) 2010-09-09 US claimed
CN-101330905-A Freeze-drying process and products obtained thereby SCIDOSE LLC (US) 2008-12-24 CN claimed
EP-1954244-A1 LYOPHILIZATION PROCESS AND PRODUCTS OBTAINED THEREBY Scidose, Llc (US) 2008-08-13 EP claimed
WO-2007061529-A1 LYOPHILIZATION PROCESS AND PRODUCTS OBTAINED THEREBY SCIDOSE LLC. (US) 2007-05-31 WO claimed
US-20070116729-A1 Lyophilization process and products obtained thereby SCIDOSE LLC 2007-05-24 US claimed
EP-1049444-B1 REDUCTION OF HAIR GROWTH GILLETTE CO (US) 2004-03-24 EP claimed
EP-1049444-A1 REDUCTION OF HAIR GROWTH THE GILLETTE COMPANY (US) 2000-11-08 EP claimed
US-6060471-A Reduction of hair growth VLSI TECHNOLOGY, INC. 2000-05-09 US claimed
WO-1999037277-A1 REDUCTION OF HAIR GROWTH THE GILLETTE COMPANY (US) 1999-07-29 WO claimed
US-4552754-A Hair cosmetic composition LION CORPORATION (JP) 1985-11-12 US claimed
US-4185106-A Pyridones as antidandruff agents HOECHST AKTIENGESELLSCHAFT (DE) 1980-01-22 US claimed