SCHEMBL708763

SCHEMBL708763

CCCCO[Si](C)(OCCCC)c1ccccc1

nearest known ligand 0.46

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
LTA4H P09960 2/20 0.46
CYP2C9 P11712 4/20 0.41
CYP2C19 P33261 4/20 0.41
CYP1A2 P05177 3/20 0.41
CYP19A1 P11511 3/20 0.41
TSHR P16473 3/20 0.39
TDP1 Q9NUW8 2/20 0.39
L3MBTL1 Q9Y468 2/20 0.39
ABCB1 P08183 1/20 0.39
CYP2D6 P10635 1/20 0.39
DUT P33316 1/20 0.36
ALDH1A1 P00352 2/20 0.36
FAAH O00519 1/20 0.36
MGLL Q99685 1/20 0.36
TLR8 Q9NR97 1/20 0.36
CYP3A4 P08684 1/20 0.36
MAPK1 P28482 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2874011 0.94 LTA4H (0.46) LTA4HCYP2C9CYP2C19CYP1A2CYP19A1
SCHEMBL17391409 0.92 LTA4H (0.44) LTA4HCYP2C9CYP2C19TSHRTDP1
SCHEMBL17391558 0.91 LTA4H (0.42) LTA4HCYP2C9CYP2C19CYP1A2CYP19A1
SCHEMBL704788 0.90 CYP2C9 (0.39) LTA4HCYP2C9CYP2C19CYP1A2CYP19A1
SCHEMBL426599 0.88 LMNA (0.38) LTA4HCYP2C9CYP2C19CYP1A2CYP19A1
SCHEMBL706997 0.84 LTA4H (0.46) LTA4HCYP2C9CYP2C19CYP1A2CYP19A1
SCHEMBL706190 0.84 LTA4H (0.46) LTA4HCYP2C9CYP2C19CYP1A2CYP19A1
SCHEMBL17391386 0.84 LTA4H (0.41) LTA4HCYP2C9CYP2C19TSHRTDP1
SCHEMBL3294085 0.82 LMNA (0.35) LTA4HCYP2C9CYP2C19CYP1A2CYP19A1
SCHEMBL431649 0.82 LTA4H (0.47) LTA4HCYP2C9CYP2C19CYP1A2CYP19A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 52 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2107951-A1 COMPOSITION AND METHOD FOR RESTORING AN ELECTRICAL CABLE AND INHIBITING CORROSION IN THE ALUMINUM CONDUCTOR CORE UTILX CORPORATION (US) 2009-10-14 EP claimed
WO-2008088618-A1 COMPOSITION AND METHOD FOR RESTORING AN ELECTRICAL CABLE AND INHIBITING CORROSION IN THE ALUMINUM CONDUCTOR CORE UTILX CORPORATION (US) 2008-07-24 WO claimed
US-20080169450-A1 COMPOSITION AND METHOD FOR RESTORING AN ELECTRICAL CABLE AND INHIBITING CORROSION IN THE ALUMINUM CONDUCTOR CORE UTILX CORPORATION (US) 2008-07-17 US claimed
US-9657039-B2 Production method for alkoxysilanes NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY (JP) 2017-05-23 US disclosed
CN-103130825-B The manufacture method of 1,3 difluoro disiloxane compounds 株式会社艾迪科 2016-12-21 CN disclosed
US-20160002271-A1 PRODUCTION METHOD FOR ALKOXYSILANES NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY (JP) 2016-01-07 US disclosed
EP-1118385-B1 METHOD FOR PRODUCING HIGH-PERFORMANCE MATERIAL HAVING PHOTOCATALYTIC FUNCTION AND DEVICE THEREFOR TOTO LTD (JP) 2015-01-21 EP disclosed
EP-2540759-B1 Thermosetting resin composition and cured product of the same DAINIPPON INK & CHEMICALS (JP) 2014-08-06 EP disclosed
EP-2436734-B1 THERMOSETTING RESIN COMPOSITE AND CURED PRODUCT THEREOF DAINIPPON INK & CHEMICALS (JP) 2014-07-23 EP disclosed
EP-2671920-A1 THERMOSETTING RESIN COMPOSITION, CURED PRODUCT THEREOF, AND INTERLAYER ADHESIVE FILM FOR PRINTED WIRING BOARD DIC Corporation (JP) 2013-12-11 EP disclosed
US-20130309489-A1 THERMOSETTING RESIN COMPOSITION, CURED PRODUCT OF THE SAME, AND INTERLAMINAR ADHESIVE FILM USED FOR PRINTED WIRING BOARD DIC CORPORATION (JP) 2013-11-21 US disclosed
WO-2000058095-A1 DIRECT DRAWING PLANOGRAPHIC PRINTING PLATE AND PREPARATION METHOD THEREFOR KODAK POLYCHROME GRAPHICS COMPANY LTD. (US) 2000-10-05 WO disclosed
CN-1259162-A Method for surface pretreatment before formation of photocatalytic hydrophilic film, and detergent and undercoat composition for use in the same TOTO LTD (JP) 2000-07-05 CN disclosed
EP-0987317-A1 METHOD FOR SURFACE PRETREATMENT BEFORE FORMATION OF PHOTOCATALYTIC HYDROPHILIC FILM, AND DETERGENT AND UNDERCOAT COMPOSITION FOR USE IN THE SAME TOTO LTD. (JP) 2000-03-22 EP disclosed
CN-1230207-A Photocatalytic hydrophilic coating compsn. TOTO LTD (JP) 1999-09-29 CN disclosed
CN-1226918-A Antifouling member and antifouling coating composition TOTO LTD (JP) 1999-08-25 CN disclosed
US-5939194-A SEMICONDUCTORS; PHOTOEXCITATION TOTO LTD. (JP) 1999-08-17 US disclosed
EP-0913447-A1 PHOTOCATALYTIC HYDROPHILIC COATING COMPOSITION TOTO LTD. (JP) 1999-05-06 EP disclosed
EP-0903389-A1 ANTIFOULING MEMBER AND ANTIFOULING COATING COMPOSITION TOTO LTD. (JP) 1999-03-24 EP disclosed
US-3948806-A Large pore silica and polymerization catalyst PHILLIPS PETROLEUM COMPANY (US) 1976-04-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160002271-A1 PRODUCTION METHOD FOR ALKOXYSILANES MSMO1, MGAM, MACO1 LTA4H 1446/4885CYP2C9 750/4885CYP2C19 1763/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.