Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | PPARG | P37231 | 1/20 | 0.49 |
| ▸ | PPARA | Q07869 | 1/20 | 0.49 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.49 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | MME | P08473 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | SCN4A | P35499 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4849974 | 0.83 | PPARG (0.51) | LMNAPPARGPPARAMTNR1AMTNR1B | |
| SCHEMBL11052073 | 0.83 | LMNA (0.53) | LMNAPPARGPPARAMTNR1AMTNR1B | |
| SCHEMBL17205664 | 0.82 | LMNA (0.44) | LMNAPPARGPPARAMTNR1AMTNR1B | |
| Ethane SCHEMBL5531789 | 0.82 | LMNA (0.49) | LMNAPPARGPPARAMTNR1AMTNR1B | |
| SCHEMBL10983129 | 0.81 | CYP1A2 (0.66) | PPARGPPARAMMECYP1A2 | |
| SCHEMBL7862959 | 0.81 | ALDH1A1 (0.52) | PPARGPPARAMTNR1AMTNR1BALOX15 | |
| SCHEMBL11134968 | 0.80 | CPA3 (0.57) | LMNAPPARGPPARAMTNR1AMTNR1B | |
| SCHEMBL5512521 | 0.79 | LMNA (0.57) | LMNAPPARGPPARAMTNR1AMTNR1B | |
| SCHEMBL11115581 | 0.79 | CYP2C19 (0.49) | LMNAPPARGPPARAMTNR1AMTNR1B | |
| SCHEMBL5514903 | 0.78 | TBXA2R (0.47) | LMNAPPARGPPARAMTNR1AMTNR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003068806-A1 | SOLID PHASE PEPTIDE SYNTHESIS ON SILICA | JOHNSON MATTHEY PLC (GB) | 2003-08-21 | — | — | WO | claimed |
| WO-2003068806-A1 | SOLID PHASE PEPTIDE SYNTHESIS ON SILICA | JOHNSON MATTHEY PLC (GB) | 2003-08-21 | — | — | WO | disclosed |