SCHEMBL5514903

SCHEMBL5514903

O=C(O)CCCC(COc1ccccc1)C(=O)O

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TBXA2R P21731 1/20 0.47
PTGER1 P34995 1/20 0.47
PTGFR P43088 1/20 0.47
PTGER3 P43115 1/20 0.47
PTGDR Q13258 1/20 0.47
CPA3 P15088 1/20 0.46
ALOX15 P16050 1/20 0.46
PPARA Q07869 3/20 0.45
MME P08473 2/20 0.45
FFAR1 O14842 2/20 0.44
FOLH1 Q04609 1/20 0.44
ALDH1A1 P00352 1/20 0.43
CYP1A2 P05177 1/20 0.43
CYP2D6 P10635 1/20 0.43
TSHR P16473 1/20 0.43
CYP2C19 P33261 1/20 0.43
LMNA P02545 1/20 0.43
PPARG P37231 1/20 0.43
MTNR1A P48039 3/20 0.43
MTNR1B P49286 3/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5508346 0.95 TBXA2R (0.49) TBXA2RPTGER1PTGFRPTGER3PTGDR
SCHEMBL11134968 0.90 CPA3 (0.57) CPA3ALOX15PPARAMMEFFAR1
SCHEMBL6885224 0.84 LMNA (0.51) TBXA2RPTGER1PTGFRPTGER3PTGDR
SCHEMBL4550642 0.84 ALOX5 (0.53) PPARAALDH1A1LMNAPPARGMTNR1A
SCHEMBL3966237 0.83 ALOX5 (0.49) PPARALMNAPPARGMTNR1AMTNR1B
SCHEMBL10582316 0.79 PKM (0.64) ALDH1A1TSHR
Ethane SCHEMBL5531789 0.79 LMNA (0.49) ALOX15PPARAMMEALDH1A1CYP2D6
SCHEMBL7087892 0.78 LMNA (0.50) ALOX15PPARAMMEALDH1A1CYP1A2
SCHEMBL11052073 0.76 LMNA (0.53) ALOX15PPARAMMEFFAR1CYP1A2
SCHEMBL4849974 0.76 PPARG (0.51) ALOX15PPARAMMECYP1A2LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1470258-B1 COMPOSITION AND ITS USE FOR IMPARTING WATER REPELLENCY TO LEATHER OR FURSKINS, TEXTILES AND OTHER FIBROUS MATERIALS TFL LEDERTECHNIK GMBH (DE) 2013-08-28 EP disclosed
US-7250456-B2 Composition and its use for imparting water repellency to leather or furskins, textiles and other fibrous materials TFL LEDERTECHNIK GMBH (DE) 2007-07-31 US disclosed
US-20050148702-A1 Composition and its use for imparting water repellency to leather or furskins, textiles and other fibrous materials TFL LEDERTECHNIK GMBH (DE) 2005-07-07 US disclosed
EP-1470258-A1 COMPOSITION AND ITS USE FOR IMPARTING WATER REPELLENCY TO LEATHER OR FURSKINS, TEXTILES AND OTHER FIBROUS MATERIALS TFL Ledertechnik GmbH (DE) 2004-10-27 EP disclosed
WO-2003064707-A1 COMPOSITIONS AND ITS USE FOR IMPARTING WATER REPELLENCY TO LEATHER OR FURSKINS, TEXTILES AND OTHER FIBROUS MATERIALS TFL LEDERTECHNIK GMBH (DE) 2003-08-07 WO disclosed