SCHEMBL7088084

SCHEMBL7088084

C=C(CC(=O)O)C(=O)OCCOCC

nearest known ligand 0.61

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.61
TSHR P16473 6/20 0.48
ALDH1A1 P00352 6/20 0.48
EGLN1 Q9GZT9 1/20 0.35
HSD17B10 Q99714 2/20 0.34
ALOX15 P16050 1/20 0.34
SMN1; SMN2 Q16637 2/20 0.33
EPHX2 P34913 1/20 0.33
CYP2D6 P10635 1/20 0.33
TP53 P04637 2/20 0.31
HIF1A Q16665 2/20 0.31
MGAM O43451 1/20 0.31
GAA P10253 1/20 0.31
SI P14410 1/20 0.31
MGAM2 Q2M2H8 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1070358 0.85 THRB (0.61) THRBTSHRALDH1A1HSD17B10SMN1; SMN2
SCHEMBL9056866 0.84 THRB (0.43) THRBTSHRALDH1A1HSD17B10
SCHEMBL481223 0.82 TSHR (0.41) THRBTSHRALDH1A1EGLN1HSD17B10
SCHEMBL111960 0.82 THRB (0.68) THRBTSHRALDH1A1HSD17B10SMN1; SMN2
SCHEMBL262250 0.82 EGLN1 (0.50) THRBTSHRALDH1A1EGLN1HSD17B10
SCHEMBL27109623 0.82 TSHR (0.51) THRBTSHREPHX2
SCHEMBL27109620 0.82 TSHR (0.51) THRBTSHREPHX2
SCHEMBL27109614 0.82 TSHR (0.51) THRBTSHREPHX2
SCHEMBL6855594 0.81 MEN1 (0.41) THRBTSHRALDH1A1HSD17B10ALOX15
SCHEMBL9480340 0.81 THRB (0.66) THRBTSHRALDH1A1HSD17B10SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11833233-B2 Alkali-swellable multi-functional rheology modifiers NOURYON CHEMICALS INTERNATIONAL B.V. (NL) 2023-12-05 US disclosed
EP-1331494-A1 COMPOSITION FOR OPTICAL MATERIAL, OPTICAL MATERIAL, AND PLASTIC LENS NOF CORPORATION (JP) 2003-07-30 EP disclosed
US-4463149-A UNSATURATED POLYSILOXANES POLYMER TECHNOLOGY CORPORATION (US) 1984-07-31 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11833233-B2 Alkali-swellable multi-functional rheology modifiers PUF60, CUTA, SMURF1 THRB 4692/4885TSHR 4052/4885ALDH1A1 3385/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.