SCHEMBL4846626

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1013650	0.83	TRPV1 (1.00)	TRPV1MAPTABL1BCR
	SCHEMBL13675611	0.82	TRPV1 (0.70)	TRPV1MAPTCLK1CLK2DYRK1A
	SCHEMBL14082702	0.79	RAB9A (0.58)	TRPV1MAPTMEN1NPC1ALDH1A1
	SCHEMBL12297542	0.78	ALOX5 (0.73)	TRPV1MAPTALOX5MEN1NPC1
	SCHEMBL4836061	0.76	TRPV1 (0.87)	TRPV1MAPTDYRK1ACLK4ABL1
	SCHEMBL7089033	0.76	TRPV1 (0.54)	TRPV1MAPTADRA2AADRA2BADRA2C
	SCHEMBL3996428	0.75	TRPV1 (0.60)	TRPV1MAPTCLK1CLK2DYRK1A
	SCHEMBL4000052	0.73	TRPV1 (0.58)	TRPV1MAPTCLK1CLK2DYRK1A
	SCHEMBL25755088	0.73	KIF11 (0.56)	TRPV1GSK3BABL1BCR
	SCHEMBL4833186	0.72	TRPV1 (0.80)	TRPV1DYRK1ACLK4ABL1BCR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.