Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 2/20 | 0.47 |
| ▸ | MAOB | P27338 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 4/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.39 |
| ▸ | FER | P16591 | 1/20 | 0.39 |
| ▸ | LTK | P29376 | 1/20 | 0.39 |
| ▸ | CDK8 | P49336 | 1/20 | 0.39 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.39 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.39 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.39 |
| ▸ | NQO1 | P15559 | 1/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7089176 | 1.00 | MAOA (0.47) | MAOAMAOBMAPTMEN1KMT2A | |
| SCHEMBL7089174 | 1.00 | MAOA (0.47) | MAOAMAOBMAPTMEN1KMT2A | |
| SCHEMBL7092480 | 0.78 | LRRK2 (0.48) | MAOAMAOBMAPTMEN1KMT2A | |
| SCHEMBL7092479 | 0.78 | LRRK2 (0.48) | MAOAMAOBMAPTMEN1KMT2A | |
| Indigo SCHEMBL42280 | 0.78 | MAOA (0.67) | MAOAMAOBMAPTMEN1KMT2A | |
| Indigo SCHEMBL29583322 | 0.78 | MAOA (0.67) | MAOAMAOBMAPTMEN1KMT2A | |
| Indigo SCHEMBL320595 | 0.78 | MAOA (0.67) | MAOAMAOBMAPTMEN1KMT2A | |
| Indigo SCHEMBL56085 | 0.78 | MAOA (0.67) | MAOAMAOBMAPTMEN1KMT2A | |
| Indigo SCHEMBL29829264 | 0.78 | MAOA (0.67) | MAOAMAOBMAPTMEN1KMT2A | |
| SCHEMBL7649436 | 0.75 | ALOX15 (0.50) | MAOAMAOBMAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030121113-A1 | Oxobenzofuranylide-dihydroindolone | NESVADBA PETER (CH) | 2003-07-03 | — | — | US | disclosed |
| US-6503937-B1 | Coloring agents for high molecular weight materials such as polymers | CIBA SPECIALTY CHEMICALS CORPORATION | 2003-01-07 | — | — | US | disclosed |
| EP-1123289-B1 | OXOBENZOFURANYLIDE-DIHYDROINDOLONES | CIBA SC HOLDING AG (CH) | 2002-11-27 | — | — | EP | disclosed |
| EP-1123289-A1 | OXOBENZOFURANYLIDE-DIHYDROINDOLONE | Ciba SC Holding AG (CH) | 2001-08-16 | — | — | EP | disclosed |
| WO-2000024736-A1 | OXOBENZOFURANYLIDE-DIHYDROINDOLONE | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2000-05-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030121113-A1 | Oxobenzofuranylide-dihydroindolone | CYP1B1, CYP1A1, ECI1 | MAOA 1624/4885MAOB 561/4885MAPT 4204/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.