Indigo

Indigo

SCHEMBL320595

O=C1C(=C2Nc3ccccc3C2=O)Nc2ccccc21

nearest known ligand 0.67

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOA P21397 2/20 0.67
MAOB P27338 1/20 0.67
LRRK2 Q5S007 2/20 0.54
PDGFRA P16234 1/20 0.54
FER P16591 1/20 0.54
LTK P29376 1/20 0.54
CDK8 P49336 1/20 0.54
ACVR1 Q04771 1/20 0.54
DYRK1B Q9Y463 1/20 0.54
MAPT P10636 9/20 0.52
ALDH1A1 P00352 6/20 0.52
MEN1 O00255 4/20 0.52
KMT2A Q03164 4/20 0.52
NPSR1 Q6W5P4 4/20 0.52
LMNA P02545 4/20 0.52
HTT P42858 3/20 0.52
HPGD P15428 2/20 0.52
TDP1 Q9NUW8 2/20 0.52
ALOX15 P16050 2/20 0.50
HSD17B10 Q99714 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Indigo SCHEMBL42280 1.00 MAOA (0.67) MAOAMAOBLRRK2PDGFRAFER
Indigo SCHEMBL29829264 1.00 MAOA (0.67) MAOAMAOBLRRK2PDGFRAFER
Indigo SCHEMBL29583322 1.00 MAOA (0.67) MAOAMAOBLRRK2PDGFRAFER
Indigo SCHEMBL56085 1.00 MAOA (0.67) MAOAMAOBLRRK2PDGFRAFER
Indirubin SCHEMBL31032717 0.83 MAOA (0.64) MAOAMAOBLRRK2PDGFRAFER
Indirubin SCHEMBL9899338 0.83 MAOA (0.64) MAOAMAOBLRRK2PDGFRAFER
Indirubin SCHEMBL30215500 0.83 MAOA (0.64) MAOAMAOBLRRK2PDGFRAFER
Indirubin SCHEMBL27678 0.83 MAOA (0.64) MAOAMAOBLRRK2PDGFRAFER
Indirubin SCHEMBL20535353 0.83 MAOA (0.64) MAOAMAOBLRRK2PDGFRAFER
Indirubin SCHEMBL6809175 0.83 MAOA (0.64) MAOAMAOBLRRK2PDGFRAFER

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 278 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240076499-A1 PROCESS FOR THE PREPARATION OF INDIGOTINDISULFONATE SODIUM (INDIGO CARMINE) PROVEPHARM LIFE SOLUTIONS S.A. (FR) 2024-03-07 US claimed
US-10927258-B2 Process for the preparation of Indigotindisulfonate sodium (indigo carmine) BIOPHORE INDIA PHARMACEUTICALS PVT. LTD. (IN) 2021-02-23 US claimed
EP-3559121-A1 NOVEL PROCESS FOR THE PREPARATION OF INDIGOTINDISULFONATE SODIUM (INDIGO CARMINE) Biophore India Pharmaceuticals Pvt. Ltd. (IN) 2019-10-30 EP claimed
WO-2018116325-A1 NOVEL PROCESS FOR THE PREPARATION OF INDIGOTINDISULFONATE SODIUM (INDIGO CARMINE) BIOPHORE INDIA PHARMACEUTICALS PVT. LTD. (IN) 2018-06-28 WO claimed
JP-4750804-B2 2011-08-17 JP claimed
US-20080306026-A1 Capsule Formulation SYNGENTA CROP PROTECTION LLC 2008-12-11 US claimed
JP-2008531514-A 2008-08-14 JP claimed
EP-1850664-A2 PESTICIDAL CAPSULE FORMULATION Syngeta Participations AG (CH) 2007-11-07 EP claimed
WO-2006089747-A2 PRESTICIDAL CAPSULE FORMULATION SYNGENTA PARTICIPATIONS AG (CH) 2006-08-31 WO claimed
US-20250213444-A1 COMPOSITION FOR ENHANCING KERATIN FIBERS WELLA GERMANY GMBH (DE) 2025-07-03 US disclosed
EP-4574216-A2 COMPOSITION FOR ENHANCING KERATIN FIBERS Wella Germany GmbH (DE) 2025-06-25 EP disclosed
US-20240415751-A1 WATER REDUCED COMPACT SHAMPOO COMPOSITION WELLA GERMANY GMBH (DE) 2024-12-19 US disclosed
US-20240415750-A1 WATER REDUCED COMPACT CONDITIONER COMPOSITION WELLA GERMANY GMBH (DE) 2024-12-19 US disclosed
CN-112384225-B Application of edible azo dye brilliant black BN in inhibiting infectivity of human enteroviruses causing hand-foot-mouth disease 淡马锡生命科学实验室有限公司 2024-06-14 CN disclosed
US-5643356-A UNSATURATED KETONE SENSITIZER BONDED TO RADIATION TRANSORBER WITH COLOR, MOLECULAR INCLUDENT AND VEHICLES KIMBERLY-CLARK CORPORATION (US) 1997-07-01 US disclosed
US-5643701-A Electrophotgraphic process utilizing mutable colored composition KIMBERLY-CLARK CORPORATION (US) 1997-07-01 US disclosed
WO-1997020000-A2 IMPROVED COLORANT STABILIZERS KIMBERLY-CLARK WORLDWIDE, INC. (US) 1997-06-05 WO disclosed
US-5616443-A TONER FOR ELECTROGRAPHY KIMBERLY-CLARK CORPORATION (US) 1997-04-01 US disclosed
WO-1996022335-A1 NOVEL COLORANTS AND COLORANT MODIFIERS KIMBERLY-CLARK WORLDWIDE, INC. (US) 1996-07-25 WO disclosed
WO-1996019502-A1 IMPROVED MUTABLE COMPOSITION KIMBERLY-CLARK WORLDWIDE, INC. (US) 1996-06-27 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250213444-A1 COMPOSITION FOR ENHANCING KERATIN FIBERS KRT18, DSG1, CUTA MAOA 1467/4885MAOB 2811/4885LRRK2 4239/4885
US-20240415751-A1 WATER REDUCED COMPACT SHAMPOO COMPOSITION PSAP, POLR1C, AQP3 MAOA 2355/4885MAOB 2873/4885LRRK2 3066/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.