Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 6/20 | 0.60 |
| ▸ | ADRB1 | P08588 | 6/20 | 0.60 |
| ▸ | ADRB3 | P13945 | 6/20 | 0.60 |
| ▸ | MEN1 | O00255 | 5/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.51 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5666047 | 0.85 | ADRB2 (0.62) | ADRB2ADRB1ADRB3MEN1KMT2A | |
| SCHEMBL5663767 | 0.85 | ADRB2 (0.59) | ADRB2ADRB1ADRB3MEN1KMT2A | |
| SCHEMBL18293614 | 0.84 | ADRB2 (0.59) | ADRB2ADRB1ADRB3MEN1KMT2A | |
| SCHEMBL5665673 | 0.82 | ADRB2 (0.54) | ADRB2ADRB1ADRB3KMT2AALDH1A1 | |
| SCHEMBL7092732 | 0.82 | ADRB2 (0.61) | ADRB2ADRB1ADRB3MEN1KMT2A | |
| SCHEMBL7089522 | 0.81 | GAA (0.44) | ADRB2ADRB1ADRB3MEN1KMT2A | |
| SCHEMBL7092852 | 0.81 | HPGD (0.43) | ADRB2ADRB1ADRB3MEN1KMT2A | |
| SCHEMBL5662710 | 0.80 | ALDH1A1 (0.56) | ADRB2ADRB1ADRB3KMT2AALDH1A1 | |
| SCHEMBL7090345 | 0.80 | ADRB2 (0.56) | ADRB2ADRB1ADRB3ALDH1A1MAPT | |
| SCHEMBL10439554 | 0.79 | ADRB2 (0.68) | ADRB2ADRB1ADRB3MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030162992-A1 | Reacting a 2,2-dialkoxyethyl halide with an appropriate carboxylate compound to obtain acetal compound; hydrolyzing the acetal to form the alpha -acyloxyacetaldehyde | PHARMASSET, INC. | 2003-08-28 | — | — | US | claimed |
| US-20030162992-A1 | Reacting a 2,2-dialkoxyethyl halide with an appropriate carboxylate compound to obtain acetal compound; hydrolyzing the acetal to form the alpha -acyloxyacetaldehyde | PHARMASSET, INC. | 2003-08-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030162992-A1 | Reacting a 2,2-dialkoxyethyl halide with an appropriate carboxylate compound to obtain acetal compound; hydrolyzing the acetal to form the alpha -acyloxyacetaldehyde | DERA, DPYD, DHPS | ADRB2 2550/4885ADRB1 2164/4885ADRB3 2653/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.