Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | ADRB2 | P07550 | 9/20 | 0.42 |
| ▸ | ADRB1 | P08588 | 9/20 | 0.42 |
| ▸ | ADRB3 | P13945 | 9/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.39 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.39 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.39 |
| ▸ | NHERF1 | O14745 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5665673 | 0.87 | ADRB2 (0.54) | NPC1RAB9AMAPTALDH1A1ADRB2 | |
| SCHEMBL7089522 | 0.85 | GAA (0.44) | MAPTALDH1A1ADRB2ADRB1ADRB3 | |
| SCHEMBL5662710 | 0.85 | ALDH1A1 (0.56) | NPC1RAB9AMAPTALDH1A1ADRB2 | |
| SCHEMBL7090345 | 0.84 | ADRB2 (0.56) | NPC1RAB9AMAPTALDH1A1ADRB2 | |
| SCHEMBL5663941 | 0.83 | MAPK1 (0.50) | HPGDNPC1RAB9AKDM4EMAPT | |
| SCHEMBL5663225 | 0.83 | NHERF1 (0.48) | HPGDNPC1RAB9AKDM4EMAPT | |
| SCHEMBL7089243 | 0.81 | ADRB2 (0.60) | KDM4EMAPTALDH1A1ADRB2ADRB1 | |
| SCHEMBL7093992 | 0.80 | HPGD (0.49) | HPGDNPC1RAB9AKDM4EMAPT | |
| SCHEMBL5664162 | 0.77 | ALDH1A1 (0.46) | HPGDNPC1RAB9AMAPTALDH1A1 | |
| SCHEMBL5663769 | 0.76 | ADRB2 (0.58) | NPC1RAB9AKDM4EALDH1A1ADRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030162992-A1 | Reacting a 2,2-dialkoxyethyl halide with an appropriate carboxylate compound to obtain acetal compound; hydrolyzing the acetal to form the alpha -acyloxyacetaldehyde | PHARMASSET, INC. | 2003-08-28 | — | — | US | claimed |
| US-20030162992-A1 | Reacting a 2,2-dialkoxyethyl halide with an appropriate carboxylate compound to obtain acetal compound; hydrolyzing the acetal to form the alpha -acyloxyacetaldehyde | PHARMASSET, INC. | 2003-08-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030162992-A1 | Reacting a 2,2-dialkoxyethyl halide with an appropriate carboxylate compound to obtain acetal compound; hydrolyzing the acetal to form the alpha -acyloxyacetaldehyde | DERA, DPYD, DHPS | HPGD 609/4885NPC1 4055/4885RAB9A 3285/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.